ReviewMaterials (Basel, Switzerland)2021
Clinical Performance of CAD/CAM All-Ceramic Tooth-Supported Fixed Dental Prostheses: A Systematic Review and Meta-Analysis.
Review in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Cytokines profile in gingival crevicular fluid of subjects wearing fixed dental prostheses: a systematic review and meta-analysis.European journal of medical research · 2024Pooled it
- Survival of Complete Coverage Tooth-Retained Fixed Lithium Disilicate Prostheses: A Systematic Review.Medicina (Kaunas, Lithuania) · 2022Pooled it
- The Use and Performance of Artificial Intelligence in Prosthodontics: A Systematic Review.Sensors (Basel, Switzerland) · 2021Pooled it
- Influence of Prosthetic Material Type on the Survival of Tooth-Supported Fixed Dental Prostheses: A Systematic Review of the Literature.Clinical, cosmetic and investigational dentistry · 2026Review
- Comparative Evaluation of Color Stability and Fracture Resistance of CAD/CAM and Chairside Provisional Restorations: An In Vitro Study.Journal of functional biomaterials · 2025Article
- Fracture resistance of chairside cad/cam advanced lithium disilicate maxillary canine veneers with different incisal edge designs.The Saudi dental journal · 2025Article
- Job Demands and Resources Perceived by Dentists in a Digital Dental Workplace and Perceived Effects on Job Satisfaction and Stress: A Qualitative Study.Clinics and practice · 2025Article
- Effects of Ceramic Shade, Ceramic Thickness, and Surface Treatment on the Color Match of High-Translucency Monolithic Multilayer Zirconia Restorations.International journal of dentistry · 2025Article
- Exploring the Practical Applications of Artificial Intelligence, Deep Learning, and Machine Learning in Maxillofacial Surgery: A Comprehensive Analysis of Published Works.Bioengineering (Basel, Switzerland) · 2024Article
- Transforming Prosthodontics and oral implantology using robotics and artificial intelligence.Frontiers in oral health · 2024Review
- Translucent Zirconia in Fixed Prosthodontics-An Integrative Overview.Biomedicines · 2023Review
- Reasons for Crown Failures in Primary Teeth: Protocol for a Systematic Review and Meta-Analysis.JMIR research protocols · 2023Article
- Translucency of Lithium-Based Silicate Glass-Ceramics Blocks for CAD/CAM Procedures: A Narrative Review.Materials (Basel, Switzerland) · 2023Review
- Accuracy of Computerized Optical Impression Making in Fabrication of Removable Dentures for Partially Edentulous Jaws: An In Vivo Feasibility Study.Journal of functional biomaterials · 2023Article
- Effectiveness of Self-Adhesive Resin Luting Cement in CAD-CAM Blocks-A Systematic Review and Meta-Analysis.Materials (Basel, Switzerland) · 2023Review
- Effect of Different Scaling Methods on the Surface Topography of Different CAD/CAM Ceramic Compositions.Materials (Basel, Switzerland) · 2023Article
- Review
- Roughness of the Surface of Zirconia Reinforced Lithium Disilicate Ceramic Treated by Different Procedures.Materials (Basel, Switzerland) · 2022Article
- Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although CAD/CAM ceramics present a promising alternative to metal-ceramic fixed dental prostheses, little is known about their mid- and long-term clinical performance. This systematic review aims to estimate the survival and success rates and describes the underlying complication characteristics for CAD/CAM tooth-supported zirconia- and lithium disilicate-based fixed dental prostheses (FDPs). We systematically searched MEDLINE and Web of Science to find relevant prospective studies with a follow-up of at least one year. We estimated pooled 1-, 5-, and 10-year survival and success rates by combining the collected data in a Poisson regression model. Descriptive statistics were conducted to evaluate the distribution of failures and complications in the included studies. Risk of bias for the included studies was assessed with an adapted checklist for single-arm trials. Pooled estimated 1-, 5-, and 10-year survival rates ranged from 93.80% to 94.66%, 89.67% to 91.1%, and 79.33% to 82.20%, respectively. The corresponding success rates excluding failures, but including any other types of intervention were 94.53% to 96.77%, 90.89% to 94.62%, and 81.78% to 89.25%. Secondary caries was the most frequent cause of failure, followed by chipping of the veneering. The most common cause of complication excluding failures but requiring intervention was chipping of the veneering. Risk of bias was generally acceptable for the included studies, with seven studies associated with low risk of bias, eight studies with a moderate risk of bias, and three studies with serious risk of bias. The current meta-analysis on CAD/CAM-supported FDPs revealed satisfying survival and success rates for up to 10 years of exposure. More prospective studies focusing on long-term performance are needed to strengthen the evidence currently available in the literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.