Evidence map›Paper›PMID 34065165›Full record

ArticleMolecules (Basel, Switzerland)2021

Design, Synthesis, and Antitumor Activity of Olmutinib Derivatives Containing Acrylamide Moiety.

Xiaohan Hu, Sheng Tang, Feiyi Yang, Pengwu Zheng, Shan Xu, Qingshan Pan, Wufu Zhu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaohan HuSchool of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China.
Sheng TangSchool of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China.
Feiyi YangSchool of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China.
Pengwu ZhengSchool of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China.
Shan XuSchool of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China.
Qingshan PanSchool of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China.
Wufu ZhuSchool of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China.ORCID 0000-0003-0862-5139

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two series of olmutinib derivatives containing an acrylamide moiety were designed and synthesized, and their IC

Indexed as

AcrylamideAntineoplastic AgentsCell Line, TumorDrug DesignDrug Screening Assays, AntitumorErbB ReceptorsHumansMolecular Docking SimulationPhosphatidylinositol 3-KinasesPiperazinesProtein Kinase InhibitorsPyrimidinesStructure-Activity RelationshipAcrylamideAntineoplastic AgentsErbB ReceptorsolmutinibPhosphatidylinositol 3-KinasesPiperazinesProtein Kinase InhibitorsPyrimidinesacrylamideEGFRinhibitorolmutinib derivatives

Identifiers

PMID34065165
PMCPMC8160875

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.