Evidence map›Paper›PMID 34065154›Full record

Trial reportNutrients2021

Health-Related Quality of Life and Experiences of Brazilian Celiac Individuals over the Course of the Sars-Cov-2 Pandemic.

Ana Luísa Falcomer, Priscila Farage, Cláudia B Pratesi, Riccardo Pratesi, Lenora Gandolfi, Eduardo Yoshio Nakano, António Raposo, Renata Puppin Zandonadi

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pharmacological insights intoFrontiers in pharmacology · 2025
    Pooled it
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  4. Article
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  8. Review
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  11. Article
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  14. COVID-19 and celiac disease: a review.Therapeutic advances in gastroenterology · 2023
    Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ana Luísa FalcomerDepartment of Nutrition, School of Health Sciences, University of Brasilia, 70910-900 Brasilia, Brazil.ORCID 0000-0003-2361-8906
Priscila FarageFaculty of Nutrition, Federal University of Goias, 74605-080 Goiânia, Brazil.
Cláudia B PratesiInterdisciplinary Laboratory of Biosciences and Celiac Disease Research Center, School of Medicine, University of Brasilia, 70910-900 Brasilia, Brazil.ORCID 0000-0003-2752-4296
Riccardo PratesiInterdisciplinary Laboratory of Biosciences and Celiac Disease Research Center, School of Medicine, University of Brasilia, 70910-900 Brasilia, Brazil.ORCID 0000-0001-6372-9024
Lenora GandolfiInterdisciplinary Laboratory of Biosciences and Celiac Disease Research Center, School of Medicine, University of Brasilia, 70910-900 Brasilia, Brazil.
Eduardo Yoshio NakanoDepartment of Statistics, University of Brasilia, 70910-900 Brasilia, Brazil.ORCID 0000-0002-9071-8512
António RaposoCBIOS (Research Center for Biosciences and Health Technologies), Universidade Lusófona de Humanidades e Tecnologias, Campo Grande 376, 1749-024 Lisboa, Portugal.ORCID 0000-0002-5286-2249
Renata Puppin ZandonadiDepartment of Nutrition, School of Health Sciences, University of Brasilia, 70910-900 Brasilia, Brazil.ORCID 0000-0003-0370-3089
Universidade de Brasília · BRUniversidade Federal de Goiás · BRUniversidade Lusófona · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the end of 2019, the world has been facing an unpredicted COVID-19 pandemic with consequences for the economy, environment, society, and health. The COVID-19 pandemic has increased the risk of death, bringing unbearable psychological pressure upon people worldwide. For celiac patients, the pandemic may represent an additional burden concerning the inherent aspects of celiac disease (CD) that compromise these individuals' quality of life (QoL). Therefore, the objective of this study was to evaluate Brazilian celiac patients' QoL during the course of the COVID-19 pandemic caused by its outbreak and rapid spread and subsequent restrictive measures in addition to the dietary restrictions and other burdens caused by CD. This country-wide cross-sectional study was conducted using a self-administered instrument previously validated in Brazilian-Portuguese to investigate the QoL of individuals with CD. Data collected through the online self-administration of the Brazilian version of the celiac disease quality of life questionnaire (CDQ) comprised 674 CD individuals' responses. Although pandemics have historically posed a challenge for Brazilian population, this period was not associated with a negative impact on Brazilian CD individuals' QoL. During the pandemic, the QoL of Brazilian's with CD was more affected by gastrointestinal aspects than emotions and social aspects and worries. Gender, age, marital status, having (or not) children, occupation, and a positive test for COVID-19 did not affect CD individuals' QoL. However, the study revealed a larger burden and diminished QoL for individuals not following a gluten-free diet and those using antidepressants. Additional research is necessary to verify how the length of the pandemic will affect celiac individuals and then compare those outcomes compare to the COVID-19 period and after.

Indexed as

Celiac DiseaseDiet, Gluten-FreeEmotionsPandemicsQuality of LifeSARS-CoV-2Surveys and QuestionnairesAdultBrazilCOVID-19Cross-Sectional StudiesFemaleHumansMaleceliac diseaseCOVID-19pandemicquality of life

Identifiers

PMID34065154
PMCPMC8151969
OpenAlexW3163298130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.