ReviewBrain sciences2021
Biological Functions of Rat Ultrasonic Vocalizations, Arousal Mechanisms, and Call Initiation.
Review in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- Self-vocalizations activate the developing auditory cortex via an intracortical pathway.Science advances · 2026Article
- High-yawning male rats are more sexually motivated when exposed to sexually receptive female rats in a multichoice sexual paradigm.IBRO neuroscience reports · 2026Article
- Correlating ultrasonic communication with behavior in a small-scale rat colony living in a naturalistic habitat.iScience · 2026Article
- Ultrasonic vocal communication of negative affective states in laboratory mice.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Shelved cages impact affective behavior in Sprague Dawley rats - implications for animal welfare.Laboratory animals · 2026Article
- Auditory cortex modulates call duration in rats.Communications biology · 2026Article
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- Article
- Differential effects of amphetamine on ultrasonic vocalizations and locomotor activity in a rat model of endogenous depression.Scientific reports · 2025Article
- How we stumbled upon the rat play vocalizations: A recollection.Behavioural brain research · 2025Article
- Predator odor stress produces sex- and subpopulation-specific increases in alcohol drinking, anxiety-like behavior, and lateral hypothalamic Crh expression.Neuropharmacology · 2025Article
- Infant rat ultrasonic vocalizations in the neurodevelopmental model of schizophrenia.Scientific reports · 2025Article
- Computational Urban Ecology of New York City Rats.bioRxiv : the preprint server for biology · 2025Article
- Rearing in a Shelved Environment Chronically Modifies Offspring Behaviour and Physiology.The European journal of neuroscience · 2025Article
- Mountable miniature microphones to identify and assign mouse ultrasonic vocalizations.Cell reports methods · 2025Article
- Conspecific presence facilitates 22-kHz ultrasonic calls in male rats exposed to cat odor.Scientific reports · 2025Article
- Dorsal column pathway is involved in tactile reward-induced affective 50-kHz ultrasonic vocalizations in rats.PloS one · 2025Article
- Male rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning.eLife · 2024Article
- Altered vocal communication in adult vasopressin-deficient Brattleboro rats.Physiology & behavior · 2024Article
- From emotional arousal to executive action. Role of the prefrontal cortex.Brain structure & function · 2024Review
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review summarizes all reported and suspected functions of ultrasonic vocalizations in infant and adult rats. The review leads to the conclusion that all types of ultrasonic vocalizations subserving all functions are vocal expressions of emotional arousal initiated by the activity of the reticular core of the brainstem. The emotional arousal is dichotomic in nature and is initiated by two opposite-in-function ascending reticular systems that are separate from the cognitive reticular activating system. The mesolimbic cholinergic system initiates the aversive state of anxiety with concomitant emission of 22 kHz calls, while the mesolimbic dopaminergic system initiates the appetitive state of hedonia with concomitant emission of 50 kHz vocalizations. These two mutually exclusive arousal systems prepare the animal for two different behavioral outcomes. The transition from broadband infant isolation calls to the well-structured adult types of vocalizations is explained, and the social importance of adult rat vocal communication is emphasized. The association of 22 kHz and 50 kHz vocalizations with aversive and appetitive states, respectively, was utilized in numerous quantitatively measured preclinical models of physiological, psychological, neurological, neuropsychiatric, and neurodevelopmental investigations. The present review should help in understanding and the interpretation of these models in biomedical research.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.