Evidence map›Paper›PMID 34065085›Full record

ArticleInternational journal of molecular sciences2021

Assessment of TSPAN Expression Profile and Their Role in the VSCC Prognosis.

Kelly Pedrozo Ferreira, Bruna Cristine de Almeida, Laura Gonzalez Dos Anjos, Glauco Baiocchi, Fernando Augusto Soares, Rafael Malagoli Rocha, Edmund Chada Baracat, Andrey Senos Dobroff, Katia Candido Carvalho

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. CouldBiomedicines · 2025
    Article
  3. Advances in Gynecological Cancers.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Kelly Pedrozo FerreiraLaboratório de Ginecologia Estrutural e Molecular (LIM 58), Disciplina de Ginecologia, Departamento de Obstetricia e Ginecologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, HCFMUSP, SP, BR Av. Dr Arnaldo 455, sala 4121, Cerqueira Cesar, São Paulo 05403-010, Brazil.
Bruna Cristine de AlmeidaLaboratório de Ginecologia Estrutural e Molecular (LIM 58), Disciplina de Ginecologia, Departamento de Obstetricia e Ginecologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, HCFMUSP, SP, BR Av. Dr Arnaldo 455, sala 4121, Cerqueira Cesar, São Paulo 05403-010, Brazil.ORCID 0000-0003-1641-5609
Laura Gonzalez Dos AnjosLaboratório de Ginecologia Estrutural e Molecular (LIM 58), Disciplina de Ginecologia, Departamento de Obstetricia e Ginecologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, HCFMUSP, SP, BR Av. Dr Arnaldo 455, sala 4121, Cerqueira Cesar, São Paulo 05403-010, Brazil.ORCID 0000-0001-9027-8281
Glauco BaiocchiDepartment of Gynecology Oncology, A. C. Camargo Cancer Center, Rua Prof Antonio Prudente 211, São Paulo 01509-001, Brazil.
Fernando Augusto SoaresDepartment of Pathology, Rede D'OR-São Luiz, Rua das Perobas, 344-Jabaquara, São Paulo 04321-120, Brazil.
Rafael Malagoli RochaDepartment of Gynecology, Federal University of São Paulo (UNIFESP), R. Napoleão de Barros, 608, Vila Clementino, São Paulo 04024-002, Brazil.
Edmund Chada BaracatLaboratório de Ginecologia Estrutural e Molecular (LIM 58), Disciplina de Ginecologia, Departamento de Obstetricia e Ginecologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, HCFMUSP, SP, BR Av. Dr Arnaldo 455, sala 4121, Cerqueira Cesar, São Paulo 05403-010, Brazil.
Andrey Senos DobroffUniversity of New Mexico Comprehensive Cancer Center (UNMCCC), 1 University of New Mexico, Albuquerque, NM 87131, USA.ORCID 0000-0003-2162-9951
Katia Candido CarvalhoLaboratório de Ginecologia Estrutural e Molecular (LIM 58), Disciplina de Ginecologia, Departamento de Obstetricia e Ginecologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, HCFMUSP, SP, BR Av. Dr Arnaldo 455, sala 4121, Cerqueira Cesar, São Paulo 05403-010, Brazil.ORCID 0000-0001-7295-678X
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRAC Camargo Hospital · BRD’Or Institute for Research and Education · BRUniversidade Federal de São Paulo · BRUniversity of New Mexico · US

Funding

Fundação de Amparo a Pesquisa do Estado de Sao Paulo 2012/17120-6 and 2015/21068-8UNM Comprehensive Cancer Center Support Grant NCI P30CA118100
6 · The paper itself

Abstract

The role and prognostic value of tetraspanins (TSPANs) in vulvar squamous cell carcinoma (VSCC) remain poorly understood. We sought to primarily determine, at both the molecular and tissue level, the expression profile of the TSPANs CD9, CD63, CD81, and CD82 in archived VSCC samples (

Indexed as

Gene Expression Regulation, NeoplasticTranscriptomeAdultAgedCarcinoma, Squamous CellDisease SusceptibilityFemaleHumansImmunohistochemistryKaplan-Meier EstimateMiddle AgedModels, BiologicalNeoplasm GradingNeoplasm StagingPrognosisRisk FactorsTetraspaninscell cultureHPV infectionimmunohistochemistryprognosissiRNAtetraspaninsVSCC

Identifiers

PMID34065085
PMCPMC8125994
OpenAlexW3160833596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.