Evidence map›Paper›PMID 34065073›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Effect of Perineural Injection with Different Dextrose Volumes on Median Nerve Size, Elasticity and Mobility in Hands with Carpal Tunnel Syndrome.

Meng-Ting Lin, I-Chun Liu, Wei-Ting Syu, Po-Ling Kuo, Chueh-Hung Wu

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06188390 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Comparing Efficacy of Hydrodissection With Hyaluronic Acid vs 5% Dextrose for Carpal Tunnel Syndrome: A Randomized Controlled Trial and Ultrasonographic Evaluation of Median Nerve Gliding

TypeinterventionalSponsorTaipei Tzu Chi Hospital, Buddhist Tzu Chi Medical FoundationRan2023 to 2024Enrolled60ConditionsCarpal Tunnel SyndromeArmsUltrasound guided median nerve hydrodissection injection with Hyaluronic acid, Ultrasound guided median nerve hydrodissection injection with Dextrose water
NCT06243848 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of Ultrasound-Guided Injection With Traditional Median Nerve Decompression Surgery in Patients With Carpal Tunnel Syndrome: Randomized Controlled Study

TypeinterventionalSponsorAfyonkarahisar Health Sciences UniversityRan2024 to 2026Enrolled60ConditionsMusculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound-Guided InjectionArmsMinimal Incision Surgery for median nerve decompression, Ultrasound-guided perineural injection with 5 cc 5% Dextrose
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meng-Ting LinDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu 300, Taiwan.ORCID 0000-0003-4796-3341
I-Chun LiuDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Wei-Ting SyuGraduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei 100, Taiwan.
Po-Ling KuoDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Chueh-Hung WuDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu 300, Taiwan.ORCID 0000-0002-3979-3541

Funding

Ministry of Science and Technology, Taiwan MOST 107-2314-B-002-045-MY3, MOST 107-2314-B-002-232-MY3National Taiwan University Hospital NTUH 108-M4366, 109-M4670
6 · The paper itself

Abstract

This study aimed to investigate the effect of different injectate volumes on ultrasonographic parameters and the correlation to clinical outcomes under perineural dextrose injection (PDI). In this post hoc analysis of the randomized, double-blinded, three-arm trial, ultrasound-guided PDI with either 1 mL, 2 mL, and 4 mL 5% dextrose water was administered, respectively, in 14, 14, and 17 patients. Ultrasound outcomes included mobility, shear-wave elastography (SWE), and cross-sectional area (CSA) of the median nerve; clinical outcomes were Visual Analog Scale (VAS) and Boston Carpal Tunnel Questionnaire (BCTQ) score. Outcomes were measured before injection, and after injection at the 1st, 4th, 12th, and 24th week. For ultrasound outcomes, CSA decreased significantly from baseline data at all follow-up time-points in the 2 mL group (

Indexed as

elasticity imaging techniquesmedian nervenerve compression syndromes

Identifiers

PMID34065073
PMCPMC8150286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.