Evidence map›Paper›PMID 34065040›Full record

ArticleMicromachines2021

3D Bioprinting of Model Tissues That Mimic the Tumor Microenvironment.

Florina Bojin, Andreea Robu, Maria Iulia Bejenariu, Valentin Ordodi, Emilian Olteanu, Ada Cean, Roxana Popescu, Monica Neagu, Oana Gavriliuc, Adrian Neagu and 2 more

Abstract read
In one paragraph

Article in Micromachines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Florina BojinDepartment of Functional Sciences, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Andreea RobuDepartment of Automation and Applied Informatics, "Politehnica" University of Timisoara, 300223 Timisoara, Romania.
Maria Iulia BejenariuFaculty of Mechanical Engineering, "Politehnica" University of Timisoara, 300222 Timisoara, Romania.
Valentin OrdodiOncoGen Institute, 300723 Timisoara, Romania.
Emilian OlteanuDepartment of Functional Sciences, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.ORCID 0000-0001-5921-4634
Ada CeanOncoGen Institute, 300723 Timisoara, Romania.
Roxana PopescuDepartment of Functional Sciences, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Monica NeaguDepartment of Functional Sciences, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Oana GavriliucDepartment of Functional Sciences, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Adrian NeaguDepartment of Functional Sciences, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.ORCID 0000-0003-3871-2188
Stelian ArjocaDepartment of Functional Sciences, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.ORCID 0000-0002-4890-6173
Virgil PăunescuDepartment of Functional Sciences, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.

Funding

Victor Babes University of Medicine and Pharmacy Timisoara 1POSTDOC/1310/31.01.2020
6 · The paper itself

Abstract

The tumor microenvironment (TME) influences cancer progression. Therefore, engineered TME models are being developed for fundamental research and anti-cancer drug screening. This paper reports the biofabrication of 3D-printed avascular structures that recapitulate several features of the TME. The tumor is represented by a hydrogel droplet uniformly loaded with breast cancer cells (10

Indexed as

breast cancerextrusion bioprintingperipheral blood mononuclear cellstumor-associated fibroblasts

Identifiers

PMID34065040
PMCPMC8151644

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.