Evidence map›Paper›PMID 34065019›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Peptide-Based Electrospun Fibers: Current Status and Emerging Developments.

Raffaella Bucci, Evangelos Georgilis, Alexander M Bittner, Maria L Gelmi, Francesca Clerici

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. ACS applied polymer materials · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raffaella BucciDepartment of Pharmaceutical Sciences, University of Milan, Via Venezian 21, 20133 Milan, Italy.ORCID 0000-0002-5465-9447
Evangelos GeorgilisCIC nanoGUNE, (BRTA) Tolosa Hiribidea 76, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-3929-5227
Alexander M BittnerCIC nanoGUNE, (BRTA) Tolosa Hiribidea 76, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0003-4815-2444
Maria L GelmiDepartment of Pharmaceutical Sciences, University of Milan, Via Venezian 21, 20133 Milan, Italy.ORCID 0000-0003-0743-5499
Francesca ClericiDepartment of Pharmaceutical Sciences, University of Milan, Via Venezian 21, 20133 Milan, Italy.ORCID 0000-0003-3483-5914

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrospinning is a well-known, straightforward, and versatile technique, widely used for the preparation of fibers by electrifying a polymer solution. However, a high molecular weight is not essential for obtaining uniform electrospun fibers; in fact, the primary criterion to succeed is the presence of sufficient intermolecular interactions, which function similar to chain entanglements. Some small molecules able to self-assemble have been electrospun from solution into fibers and, among them, peptides containing both natural and non-natural amino acids are of particular relevance. Nowadays, the use of peptides for this purpose is at an early stage, but it is gaining more and more interest, and we are now witnessing the transition from basic research towards applications. Considering the novelty in the relevant processing, the aim of this review is to analyze the state of the art from the early 2000s on. Moreover, advantages and drawbacks in using peptides as the main or sole component for generating electrospun nanofibers will be discussed. Characterization techniques that are specifically targeted to the produced peptide fibers are presented.

Indexed as

electrospinningpeptide-based electrospun nanofiberspeptidespeptidomimeticsself-assembly

Identifiers

PMID34065019
PMCPMC8151459

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.