Evidence map›Paper›PMID 34064986›Full record

ArticleTropical medicine and infectious disease2021

Cholera Hot-Spots and Contextual Factors in Burundi, Planning for Elimination.

Amanda K Debes, Allison M Shaffer, Thaddee Ndikumana, Iteka Liesse, Eric Ribaira, Clement Djumo, Mohammad Ali, David A Sack

Abstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Identification of priority areas for cholera control, Cameroon.Bulletin of the World Health Organization · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Unmasking the Neglected Cholera Outbreaks in Sub-Saharan Africa.International journal of public health · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Contrasting Epidemiology of Cholera in Bangladesh and Africa.The Journal of infectious diseases · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amanda K DebesDepartment of International Health, Johns Hopkins School of Public Health, Baltimore, MD 21205, USA.
Allison M ShafferDepartment of International Health, Johns Hopkins School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0002-2141-7097
Thaddee NdikumanaMinistry of Public Health, Rue Pierre Ngendandumwe, Bujumbura B.P. 1650, Burundi.
Iteka LiesseMinistry of Public Health, Rue Pierre Ngendandumwe, Bujumbura B.P. 1650, Burundi.ORCID 0000-0002-4218-8561
Eric RibairaUNICEF Burundi Country Office, Bujumbura B.P. 1650, Burundi.
Clement DjumoUNICEF Burundi Country Office, Bujumbura B.P. 1650, Burundi.
Mohammad AliDepartment of International Health, Johns Hopkins School of Public Health, Baltimore, MD 21205, USA.
David A SackDepartment of International Health, Johns Hopkins School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0002-9338-5119

Funding

Epidemiology and Ecology of Cholera in AfricaR01AI123422 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Amanda Kay Debes, DAVID A SACK · 2017 to 2026
$6.6M
NIAID NIH HHS R01 AI123422NIH HHS R01AI123422
6 · The paper itself

Abstract

The Republic of Burundi first reported cholera cases in 1978 and outbreaks have been occurring nearly every year since then. From 2008-2020, 6949 cases and 43 deaths were officially reported. To evaluate Burundi's potential to eliminate cholera, we identified hotspots using cholera incidence and disease persistence as suggested by the Global Task Force for Cholera Control. The mean annual incidence for each district that reported cholera ranged from 0.29 to 563.14 cases per 100,000 population per year from 2014-2020. Ten of 12 Health Districts which recorded cholera cases reported a mean annual incidence ≥5 per 100,000 for this time period. Cholera cases occur during the second half of the year in the areas near Lake Tanganyika and along the Ruzizi River, with the highest risk district being Bujumbura Centre. Additional research is needed to understand the role of Lake Tanganyika; risks associated with fishing; migration patterns; and other factors that may explain cholera's seasonality. Due to the consistent epidemiological pattern and the relatively small area affected by cholera, control and elimination are feasible with an integrated program of campaigns using oral cholera vaccine over the short term and community-based interventions including WASH activities for sustained control.

Indexed as

Burundicholeradiarrheahot spotoral cholera vaccine

Identifiers

PMID34064986
PMCPMC8163194

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.