Evidence map›Paper›PMID 34064967›Full record

ArticleInternational journal of environmental research and public health2021

Air Pollution, Neonatal Immune Responses, and Potential Joint Effects of Maternal Depression.

Jill Hahn, Diane R Gold, Brent A Coull, Marie C McCormick, Patricia W Finn, David L Perkins, Sheryl L Rifas Shiman, Emily Oken, Laura D Kubzansky

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jill HahnDepartment of Social and Behavioral Sciences, The Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.ORCID 0000-0001-5660-3909
Diane R GoldChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Brent A CoullDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Marie C McCormickDepartment of Social and Behavioral Sciences, The Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Patricia W FinnDivision of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
David L PerkinsDivision of Nephrology, Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
Sheryl L Rifas ShimanDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA.
Emily OkenDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, USA.
Laura D KubzanskyDepartment of Social and Behavioral Sciences, The Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Harvard University · USUniversity of Illinois Chicago · USBrigham and Women's Hospital · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
Prenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6M
Effect of Ambient Particles on Acute Stroke OnsetP01ES009825 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI GOLD, DIANE R · 1999 to 2009
$17.4M
The Fetal and Childhood Environment, Oxidative Balance, Inflammation and AsthmaR01AI102960 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R, OKEN, EMILY · 2013 to 2017
$4.0M
NIEHS NIH HHS P30 ES000002NIH HHS P01ES009825NIH HHS P30ES000002NIH HHS R01AI102960NIH HHS R01 HD 034568
6 · The paper itself

Abstract

Prenatal maternal exposure to air pollution may cause adverse health effects in offspring, potentially through altered immune responses. Maternal psychosocial distress can also alter immune function and may increase gestational vulnerability to air pollution exposure. We investigated whether prenatal exposure to air pollution is associated with altered immune responses in cord blood mononuclear cells (CBMCs) and potential modification by maternal depression in 463 women recruited in early pregnancy (1999-2001) into the Project Viva longitudinal cohort. We estimated black carbon (BC), fine particulate matter (PM

Indexed as

Air PollutantsAir PollutionDepressionFemaleHumansImmunityInfant, NewbornMaternal ExposureParticulate MatterPregnancyAir PollutantsParticulate Matterair pollutionchemical stressorscord blood mononuclear cellscytokinesimmune systemintergenerational effectsmaternal prenatal depressionnon-chemical stressorssocial determinants of health

Identifiers

PMID34064967
PMCPMC8150899
OpenAlexW3160179421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.