Evidence map›Paper›PMID 34064944›Full record

ArticleCells2021

Dissecting the RecA-(In)dependent Response to Mitomycin C in

Anna Brzostek, Przemysław Płociński, Alina Minias, Aneta Ciszewska, Filip Gąsior, Jakub Pawełczyk, Bożena Dziadek, Marcin Słomka, Jarosław Dziadek

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Structure andmBio · 2024
    Article
  3. Article
  4. ZnACS omega · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Metabolites · 2021
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anna BrzostekInstitute of Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.ORCID 0000-0002-7335-9853
Przemysław PłocińskiInstitute of Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.ORCID 0000-0002-6623-3494
Alina MiniasInstitute of Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.ORCID 0000-0002-3210-6737
Aneta CiszewskaInstitute of Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.
Filip GąsiorInstitute of Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.ORCID 0000-0003-2703-764X
Jakub PawełczykInstitute of Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.ORCID 0000-0001-6863-8594
Bożena DziadekDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland.
Marcin SłomkaBiobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Łódź, Pomorska 139, 90-235 Łódź, Poland.ORCID 0000-0002-7906-5549
Jarosław DziadekInstitute of Medical Biology of the Polish Academy of Sciences, Lodowa 106, 93-232 Łódź, Poland.ORCID 0000-0003-1427-884X
Institute for Medical Biology · PLUniversity of Łódź · PL

Funding

National Science Center, Poland UMO-2015/19/B/NZ6/02978National Science Center, Poland UMO-2019/33/B/NZ1/02770
6 · The paper itself

Abstract

Mycobacteria exploit at least two independent global systems in response to DNA damage: the LexA/RecA-dependent SOS response and the PafBC-regulated pathway. Intracellular pathogens, such as

Indexed as

Bacterial ProteinsDNA DamageDNA RepairGene Expression ProfilingGene Expression Regulation, BacterialHumansLexA Repressor ProteinMacrophagesMitomycinMycobacterium tuberculosisProteomicsRec A RecombinasesSerine EndopeptidasesTranscriptional ActivationTranscription, GeneticTuberculosisBacterial ProteinsLexA Repressor ProteinMitomycinRec A RecombinasesSerine EndopeptidasesDNA damage repairSOS responsetuberculosis

Identifiers

PMID34064944
PMCPMC8151990
OpenAlexW3161315471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.