Evidence map›Paper›PMID 34064775›Full record

ArticleVaccines2021

Bladder Cancer Immunotherapy by BCG Is Associated with a Significantly Reduced Risk of Alzheimer's Disease and Parkinson's Disease.

Danielle Klinger, Brian L Hill, Noam Barda, Eran Halperin, Ofer N Gofrit, Charles L Greenblatt, Nadav Rappoport, Michal Linial, Hervé Bercovier

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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  12. Redox modulation of the complement cascade contributes to synapse loss in Alzheimer's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Danielle KlingerDepartment of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Brian L HillDepartment of Computer Science, University of California Los Angeles, Los Angeles, CA 90095-1596, USA.ORCID 0000-0002-6881-5770
Noam BardaClalit Research Institute, Innovation Division, Clalit Health Services, Ramat-Gan 6578898, Israel.ORCID 0000-0002-3400-235X
Eran HalperinDepartment of Computer Science, University of California Los Angeles, Los Angeles, CA 90095-1596, USA.
Ofer N GofritDepartment of Urology, Hadassah University Hospital, Jerusalem 91904, Israel.ORCID 0000-0001-8815-6488
Charles L GreenblattDepartment of Microbiology and Molecular Genetics, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
Nadav RappoportDepartment of Software and Information Systems Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel.ORCID 0000-0002-7218-2558
Michal LinialDepartment of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0002-9357-4526
Hervé BercovierDepartment of Microbiology and Molecular Genetics, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.ORCID 0000-0001-7297-3029
Hebrew University of Jerusalem · ILUniversity of California, Los Angeles · USBen-Gurion University of the Negev · ILHadassah Academic College · ILHarvard University · US

Funding

Israel Science Foundation 2753/20
6 · The paper itself

Abstract

Bacillus Calmette-Guerin (BCG) is a live attenuated form of

Indexed as

Bacillus Calmette–Guérinimmunotherapyneurodegenerative diseasenon-muscle-invasive bladder cancer (NMIBC)tuberculosis

Identifiers

PMID34064775
PMCPMC8151667
OpenAlexW3160295470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.