Evidence map›Paper›PMID 34064746›Full record

ArticlePharmaceutics2021

How to Achieve High Encapsulation Efficiencies for Macromolecular and Sensitive APIs in Liposomes.

Kirsten Ullmann, Gero Leneweit, Hermann Nirschl

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
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  7. Nucleated synthetic cells with genetically driven intercompartment communication.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Fabrication of Phytosome with Enhanced Activity ofInternational journal of nanomedicine · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kirsten UllmannInstitute of Mechanical Process Engineering and Mechanics, Process Machines, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany.ORCID 0000-0002-5616-5950
Gero LeneweitCarl Gustav Carus-Institute, Association for the Promotion of Cancer Therapy, 75223 Niefern-Oeschelbronn, Germany.ORCID 0000-0002-3783-1217
Hermann NirschlInstitute of Mechanical Process Engineering and Mechanics, Process Machines, Karlsruhe Institute of Technology (KIT), 76131 Karlsruhe, Germany.
Karlsruhe Institute of Technology · DEAbnoba (Germany) · DE

Funding

Phospholipid Research Center HNI-2019-072/2-1
6 · The paper itself

Abstract

This research highlights the capacity of a newly introduced centrifugation process to form liposomes from water-in-fluorocarbon nano-emulsions stabilized with phospholipids to incorporate macromolecular and sensitive active pharmaceutical ingredients (API). The encapsulation efficiency of the produced liposomes, incorporating fluorescein-sodium, bovine serum albumin and fluorecein isothiocyanate dextran as model APIs, is determined by applying Vivaspin

Indexed as

active pharmaceutical ingredientsencapsulation efficiencyfluorocarbonliposomesnano-emulsionsphospholipids

Identifiers

PMID34064746
PMCPMC8150985
OpenAlexW3163597887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.