ArticleMetabolites2021
A Comprehensive Targeted Metabolomics Assay for Crop Plant Sample Analysis.
Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Assembling an Expanded Metabolome for Camu-Camu (Myrciaria Dubia): Bioactive and Nutritional Compounds Relevant to Functional Food Research.Molecules (Basel, Switzerland) · 2026Article
- Establishment & characterization of a non-adherent insect cell line for cultivated meat.Scientific reports · 2025Article
- Effects of Growth Stages on Leaf Nutrients, Metabolites, and Polyphenols of Three Varieties of Haskap.Foods (Basel, Switzerland) · 2024Article
- Chemical Composition of Commercial Cannabis.Journal of agricultural and food chemistry · 2024Article
- Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer.Nature communications · 2024Article
- Changes in primary metabolism and associated gene expression during host-pathogen interaction in clubroot resistance of Brassica napus.PloS one · 2024Article
- Can Metabolomic Approaches Become a Tool for Improving Early Plant Disease Detection and Diagnosis with Modern Remote Sensing Methods? A Review.Sensors (Basel, Switzerland) · 2023Review
- [Research advances on burn blister fluid].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022Article
- Exact mass GC-MS analysis: Protocol, database, advantages and application to plant metabolic profiling.Plant, cell & environment · 2022Article
- Recent advances in proteomics and metabolomics in plants.Molecular horticulture · 2022Review
- Molecular and Physiological Responses ofInternational journal of molecular sciences · 2022Article
- Physiology and metabonomics reveal differences in drought resistance among soybean varieties.Botanical studies · 2022Article
- Development and Comprehensive SPE-UHPLC-MS/MS Analysis Optimization, Comparison, and Evaluation of 2,4-Epibrassinolide in Different Plant Tissues.Molecules (Basel, Switzerland) · 2022Article
- Mepiquat chloride inhibits soybean growth but improves drought resistance.Frontiers in plant science · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
Metabolomics plays an important role in various fields from health to agriculture. However, the comprehensive quantitative metabolomic analysis of plants and plant metabolites has not been widely performed. Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS)-based plant metabolomics offers the sensitivity and breadth of coverage for both phenotyping and disease diagnosis of plants. Here, we report a high-coverage and quantitative MS-based assay for plant metabolite analysis. The assay detects and quantifies 206 primary and secondary plant metabolites, including many key plant hormones. In total, it measures 28 amino acids and derivatives, 27 organic acids, 20 biogenic amines and derivatives, 40 acylcarnitines, 90 phospholipids and C-6 sugars. All the analysis methods in this assay are based on LC-MS/MS techniques using both positive and negative-mode multiple reaction monitoring (MRM). The recovery rates of spiked plant samples at three different concentration levels (low, medium and high) ranged from 80% to 120%, with satisfactory precision values of less than 20%. This targeted plant metabolomic assay has been successfully applied to the analysis of large numbers of pine and spruce needle samples, canola root samples, as well as cannabis samples. Moreover, the assay was specifically developed in a 96-well plate format, which enables automated, high-throughput sample analysis. This assay has already been used to analyze over 1500 crop plant samples in less than two months.
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