Evidence map›Paper›PMID 34064658›Full record

ArticleAnimals : an open access journal from MDPI2021

Effects of Activated Charcoal on Growth, Immunity, Oxidative Stress Markers, and Physiological Responses of Nile Tilapia Exposed to Sub-Lethal Imidacloprid Toxicity.

Samah A A Abd El-Hameed, Samar S Negm, Nahla E M Ismael, Mohammed A E Naiel, Mohamed Mohamed Soliman, Mustafa Shukry, Hany M R Abdel-Latif

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Samah A A Abd El-HameedFish Health and Management Department, Central Laboratory for Aquaculture Research (CLAR), Agriculture Research Center, Abbassa, Abu Hammad, Sharkia 44661, Egypt.
Samar S NegmFish Biology and Ecology Department, Central Laboratory for Aquaculture Research (CLAR), Agriculture Research Center, Abbassa, Abu Hammad, Sharkia 44661, Egypt.
Nahla E M IsmaelFish Biology and Ecology Department, Central Laboratory for Aquaculture Research (CLAR), Agriculture Research Center, Abbassa, Abu Hammad, Sharkia 44661, Egypt.
Mohammed A E NaielDepartment of Animal Production, Faculty of Agriculture, Zagazig University, Zagazig 44511, Egypt.ORCID 0000-0002-8172-5366
Mohamed Mohamed SolimanClinical Laboratory Sciences Department, Turabah University College, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0001-7208-7123
Mustafa ShukryDepartment of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.ORCID 0000-0003-2722-2466
Hany M R Abdel-LatifDepartment of Poultry and Fish Diseases, Faculty of Veterinary Medicine, Alexandria University, Alexandria 22758, Egypt.ORCID 0000-0001-8761-1493
Alexandria University · EGKafrelsheikh University · EGTaif University · SAZagazig University · EG

Funding

We deeply thank Taif University for the financial assistance for the Taif University Researchers Supporting Project (TURSP-2020/09), Taif University, Taif, Saudi Arabia TURSP-2020/09
6 · The paper itself

Abstract

The existing study was designed to assess the influences of dietary activated charcoal (AC) on the growth performance, immune responses, antioxidative status, and its mitigating roles against the physiological responses of Nile tilapia exposed a sub-lethal dose of a neonicotinoid agriculture pesticide, namely, as imidacloprid (IMID). Nile tilapia juveniles were fed on diets supplemented with graded AC levels as 0 (control), 5, 10, 15, and 20 g/kg diet for eight weeks. Growth, hemato-biochemical indices, and antioxidant and immune responses of fish in all groups were evaluated at the end of the feeding experiment. Afterward, fish in all experimental groups were subjected to a sub-lethal dose of IMID (0.0109 μg/L) for two weeks. Then, fish mortalities, stress indicators, and IMID residual levels in liver and flesh were examined. Results of the feeding experiment showed that total feed intake, weight gain, final body weights, and feed efficiency ratio were significantly increased in all AC groups compared with the control group. The survival rate was 100% in all experimental groups. No statistical differences were observed in the hematological picture of all experimental groups except the lymphocyte count, which was significantly increased in all AC groups compared to the control group. Total protein, albumin, globulin, nitric oxide levels, lysozyme, and respiratory burst activities were significantly increased in all AC groups. Serum alanine transaminase, aspartate transaminase, alkaline phosphatase activities, and malondialdehyde (MDA) levels were significantly decreased in all AC groups compared with the AC0 group. After exposure to a sub-lethal dose of IMID, survival rates were significantly elevated, and IMID residual levels in liver and flesh were significantly decreased in all AC groups than in the control group. Moreover, second-order polynomial regression showed that dietary supplementation with 14.30 g AC/kg diet resulted in the lowest blood glucose and serum MDA levels. Conclusively, we suggest dietary supplementation with 14.30 g AC/kg diet to modulate physiological responses of Nile tilapia to sub-lethal IMID toxicity.

Indexed as

antioxidanthematologylysozymenitric oxideOreochromis niloticus

Identifiers

PMID34064658
PMCPMC8151804
OpenAlexW3160390687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.