ArticleAnimals : an open access journal from MDPI2021
Changes in Diarrhea Score, Nutrient Digestibility, Zinc Utilization, Intestinal Immune Profiles, and Fecal Microbiome in Weaned Piglets by Different Forms of Zinc.
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 61 citations in OpenAlex.
- Zinc oxide quantum dots as an alternative to conventional ZnO: Physicochemical characterization and its application in weaned piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Maternal bis-glycinate bound zinc supplementation alters sow performance and milk metabolomic-lipidomic profiles and mitigates piglet diarrhea.Veterinary and animal science · 2026Article
- Effects of zinc supplementation forms (ZnO, Zn-Lysine, Nano-ZnO) on growth performance and metabolic health in pre-weaned Holstein calves.Scientific reports · 2026Article
- Identifying the optimal ratios for replacing spray-dried plasma protein with hydrolyzed porcine intestinal protein in weaning pig.Journal of animal science and technology · 2026Article
- Nano Zinc Oxide Improves Growth Rate, Carcass Traits, Meat Chemical Composition, Serum and Tissue Mineral Profiles, Mineral Retention, and Intestinal Morphology in Broiler Chickens Compared to Inorganic and Organic Zinc.Biological trace element research · 2026Article
- Dietary coated copper and zinc improved growth performance by modulating immune responses and fecal microbiota of weaned pigs.Journal of animal science and technology · 2025Article
- Impacts of zinc caproate supplementation on growth performance, intestinal health, anti-inflammatory activity, and Zn homeostasis in weaned piglets challenged with Escherichia coli K88.Journal of animal science and biotechnology · 2025Article
- Different sources and dosages of zinc oxide and copper influence growth performance and intestinal health of post-weaning piglets.Journal of animal science · 2025Article
- Supplementation of zinc-chelating peptides fromFrontiers in nutrition · 2025Article
- The effects of short-term intake of dietary zinc nanoparticles on plasma mineral and antioxidant status, nutrient digestibility, and intestinal microbiota in lambs.Frontiers in veterinary science · 2025Article
- Review
- The Mechanism of Zinc Oxide in Alleviating Diarrhea in Piglets after Weaning: A Review from the Perspective of Intestinal Barrier Function.International journal of molecular sciences · 2024Review
- Effects of phytogenic feed additives in growing and finishing pigs under different stocking density.Journal of animal science and technology · 2024Article
- Effects of dietary zinc on the gut microbiome and resistome of the gestating cow and neonatal calf.Animal microbiome · 2024Article
- Impact of Nutritional Strategies to Prevent Post-Weaning Diarrhoea on Performance, Behaviour, and Microbiota in Piglets from Organic Farming.Animals : an open access journal from MDPI · 2024Article
- Effects of Tetrabasic Zinc Chloride on the Diarrhea Rate, Intestinal Morphology, Immune Indices and Microflora of Weaned Piglets.Animals : an open access journal from MDPI · 2024Article
- Alternatives to antibiotics in pig production: looking through the lens of immunophysiology.Stress biology · 2024Review
- Comparison of the effects of zinc oxide and zinc aspartic acid chelate on the performance of weaning pigs.Journal of animal science and technology · 2024Article
- The Effect of Sodium Alginate-Coated Nano-Zinc Oxide on the Growth Performance, Serum Indexes and Fecal Microbial Structure of Weaned Piglets.Animals : an open access journal from MDPI · 2023Article
- Piglet growth performance improved by dietary supplementation of porous or nano particles of zinc oxide may be related to the gut microbiota.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Twenty weaned piglets with initial body weight of 6.83 ± 0.33 kg (21 day of age, LYD) were randomly assigned to four treatments for a two-week feeding trial to determine the effects of different dietary zinc on nutrient digestibility, intestinal health, and microbiome of weaned piglets. The dietary treatments included a negative control (CON), standard ZnO (ZnO, 2500 ppm), zinc chelate with glycine (Chelate-ZnO, 200 ppm), and nanoparticle-sized ZnO (Nano-ZnO, 200 ppm). At 0 to 1 week, the diarrhea score was decreased in the CON group compared with the ZnO, Chelate-ZnO, and Nano-ZnO group. In overall period, the ZnO and Nano-ZnO groups exhibited improved diarrhea scores compared to the CON group. The apparent total tract digestibility of dry matter and gross energy was the lowest in the CON group after one week. Compared to the ZnO group, the chelate-ZnO group exhibited higher proportion of T-bet+ and FoxP3+ T cells and the nano-ZnO group had higher numbers of RORgt+ and GATA3+ T cells in the mesenteric lymph nodes. ZnO group increased IL-6 and IL-8 levels in the colon tissues and these positive effects were observed in both chelate ZnO and nano-ZnO groups with lower level. The 16S rRNA gene analysis showed that the relative abundance of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.