Evidence map›Paper›PMID 34064524›Full record

ArticleFoods (Basel, Switzerland)2021

Nisin-Loaded Ulvan Particles: Preparation and Characterization.

Ruta Gruskiene, Tatjana Kavleiskaja, Ramune Staneviciene, Stefanos Kikionis, Efstathia Ioannou, Elena Serviene, Vassilios Roussis, Jolanta Sereikaite

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ruta GruskieneDepartment of Chemistry and Bioengineering, Vilnius Gediminas Technical University, 10221 Vilnius, Lithuania.
Tatjana KavleiskajaInstitute of Chemistry, Vilnius University, 01513 Vilnius, Lithuania.
Ramune StanevicieneLaboratory of Genetics, Institute of Botany, Nature Research Centre, 08412 Vilnius, Lithuania.
Stefanos KikionisSection of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.ORCID 0000-0002-0599-7490
Efstathia IoannouSection of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.ORCID 0000-0003-3103-4951
Elena ServieneDepartment of Chemistry and Bioengineering, Vilnius Gediminas Technical University, 10221 Vilnius, Lithuania.ORCID 0000-0003-0875-0538
Vassilios RoussisSection of Pharmacognosy and Chemistry of Natural Products, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.ORCID 0000-0001-9856-4725
Jolanta SereikaiteDepartment of Chemistry and Bioengineering, Vilnius Gediminas Technical University, 10221 Vilnius, Lithuania.ORCID 0000-0003-0888-2178
National and Kapodistrian University of Athens · GRVilnius Gediminas Technical University · LTNature Research Centre · LTVilnius University · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nisin is an attractive alternative to chemical preservatives in the food industry. It is a cationic peptide of 34 amino acid residues that exhibits antimicrobial activity against Gram-positive bacteria. To ensure nisin stability in food matrices, new nisin-loaded ulvan particles were developed by the complexation method. The interaction of nisin with ulvan was demonstrated by FT-IR spectroscopy and differential scanning calorimetry. The encapsulation efficiency was calculated at different pH values within the range of 4.0-7.0 and was found to have the highest value at pH 7.0. The size and surface charge of particles fabricated at different concentrations of nisin and pH values were determined. Nisin-loaded ulvan particles exhibited antimicrobial activity against Gram-positive bacteria comparable to that of free nisin. Therefore, the developed complexes have the potential for application as biopreservatives in the food industry. For the first time, the potential of ulvan as a carrier of antimicrobial agent nisin was demonstrated.

Indexed as

antimicrobial activityencapsulationnisinulvan

Identifiers

PMID34064524
PMCPMC8147952
OpenAlexW3158589744

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.