Evidence map›Paper›PMID 34064455›Full record

ArticleVaccines2021

Age-Specific Seasonal Influenza Vaccine Effectiveness against Different Influenza Subtypes in the Hospitalized Population in Lithuania during the 2015-2019 Influenza Seasons.

Monika Kuliese, Aukse Mickiene, Ligita Jancoriene, Birute Zablockiene, Giedre Gefenaite, Study Group

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Monika KulieseDepartment of Infectious Diseases, Lithuanian University of Health Sciences, Baltijos Street 120, 47116 Kaunas, Lithuania.ORCID 0000-0002-4601-4585
Aukse MickieneDepartment of Infectious Diseases, Lithuanian University of Health Sciences, Baltijos Street 120, 47116 Kaunas, Lithuania.
Ligita JancorieneClinic of Infectious Diseases and Dermatovenerology, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University, Santariskiu Street 14, 08406 Vilnius, Lithuania.ORCID 0000-0001-6488-6312
Birute ZablockieneClinic of Infectious Diseases and Dermatovenerology, Faculty of Medicine, Institute of Clinical Medicine, Vilnius University, Santariskiu Street 14, 08406 Vilnius, Lithuania.
Giedre GefenaiteDepartment of Infectious Diseases, Lithuanian University of Health Sciences, Baltijos Street 120, 47116 Kaunas, Lithuania.
Study Group
Lithuanian University of Health Sciences · LTVilnius University · LT

Funding

Functional Imaging of Hippocampal Subfields in Healthy AgingR03AG032015 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI STARK, CRAIG E · 2008 to 2009
$130k
European Commission Horizon 2020 program 634446I-MOVE+ (Influenza Monitoring Vaccines Effectiveness in Europe in Elderly) NetworkResearch Council of Lithuania agreement No. SEN-03/2015
6 · The paper itself

Abstract

backgroundContinuous monitoring of seasonal influenza vaccine effectiveness (SIVE) is needed due to the changing nature of influenza viruses and it supports the decision on the annual update of vaccine composition. Age-specific SIVE was evaluated against different influenza subtypes in the hospitalized population in Lithuania during four influenza seasons.

methodsA test-negative case-control study design was used. SIVE and its 95% confidence intervals (95% CI) were calculated as (1 - odds ratio (OR)) × 100%.

resultsAdjusted SIVE in 18-64-year-old individuals against influenza A, A(H1N1)pdm09 and B/Yamagata were 78.0% (95% CI: 1.7; 95.1%), 88.6% (95% CI: -47.4; 99.1%), and 76.8% (95% CI: -109.9; 97.4%), respectively. Adjusted SIVE in individuals aged 65 years and older against influenza A, influenza B, and B/Yamagata were 22.6% (95% CI: -36.5; 56.1%), 75.3% (95% CI: 12.2; 93.1%) and 73.1% (95% CI: 3.2; 92.5%), respectively. Unadjusted SIVE against influenza A(H3N2) among 18-64-year-old patients was 44.8% (95% CI: -171.0; 88.8%) and among those aged 65 years and older was 5.0% (95% CI: -74.5; 48.3%).

conclusionsPoint estimates suggest high SIVE against influenza A in 18-64-year-old participants, and against influenza B and B/Yamagata in those 65 years old and older.

Indexed as

hospital surveillanceinfluenzalaboratory-confirmedolder peoplerisk groupssevere outcomesunderlying conditions

Identifiers

PMID34064455
PMCPMC8147944
OpenAlexW3160233531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.