ReviewJournal of clinical medicine2021
Cardiovascular Implications of Sleep Bruxism-A Systematic Review with Narrative Summary and Future Perspectives.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Manual Therapy in Indirect Non-Invasive Neuromodulation of the Vagus Nerve in the Treatment of Bruxism in Young Adult Population up to 40 Years Old
Efficacy of Manual Therapy in Indirect Non-Invasive Neuromodulation of the Vagus Nerve in the Treatment of Bruxism in Young Adult Population up to 40 Years Old
Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Sleep Bruxism: A Narrative Review of Current Concepts, Mechanisms, and Clinical Implications.Journal of the Royal Society of New Zealand · 2026Review
- Advances in research on dental occlusion and brain function: neuroimaging correlates and molecular mechanisms.Frontiers in neurology · 2026Review
- Relational study between sleep quality, daytime sleepiness state, anxiety, stress, depression in possible bruxist and non-bruxist: cross-sectional study.Odontology · 2026Article
- Tenascin-C and Thrombospondin-1 as a Potential Link Between Sleep Bruxism and Cardiovascular Diseases-A Case-Control Study.Journal of clinical medicine · 2025Article
- Cardiovascular Risk Profiles of Individuals with Bruxism: A Case-Control Study Using QRISK3 Scores.Cureus · 2025Article
- Collaboration Between Endocrinologists and Dentists in the Care of Patients with Acromegaly-A Narrative Review.Journal of clinical medicine · 2025Review
- Short-Term Effects of Visceral Manual Therapy on Autonomic Nervous System Modulation in Individuals with Clinically Based Bruxism: A Randomized Controlled Trial.Dentistry journal · 2025Article
- Short-Term Observation of Heart Rate and Oxygen Saturation in Relation to Masticatory Muscle Activity in Temporomandibular Disorders.Brain sciences · 2025Article
- The link between sleep bruxism and oxidative stress based on a polysomnographic study.Scientific reports · 2025Article
- Arginase and ceruloplasmin activity in the serum of patients with polysomnography-detected sleep bruxism.Frontiers in neurology · 2025Article
- The Importance of Genetic Background and Neurotransmission in the Pathogenesis of the Co-Occurrence of Sleep Bruxism and Sleep-Disordered Breathing-Review of a New Perspective.Journal of clinical medicine · 2024Review
- Ambulatory devices to detect sleep bruxism: a narrative review.Australian dental journal · 2024Review
- Comparative evaluation of salivary melatonin levels in patients with bruxism: a case-control study.Biomarkers in medicine · 2024Article
- Why am I grinding and clenching? Exploration of personality traits, coping strategies, oral parafunctional behaviors, and severe sleep bruxism in a polysomnographic study.Frontiers in psychiatry · 2024Article
- Sex Differences in the Relationship Between Self-Reporting of Snoring and Cardiovascular Risk:An Analysis of NHANES.Nature and science of sleep · 2024Article
- Prevalence and Severity of Sleep Bruxism in Edentulous Patients: A Cross-Sectional Study.International journal of dentistry · 2024Article
- Systematic Review on the Link between Sleep Bruxism and Systemic Chronic Inflammation.Brain sciences · 2023Review
- Salivary signatures of oral-brain communication in sleep bruxers.Frontiers in cellular and infection microbiology · 2023Article
- Sleep Bruxism Contributes to Motor Activity Increase during Sleep in Apneic and Nonapneic Patients-A Polysomnographic Study.Biomedicines · 2022Article
- Polysomnographic Evaluation of Sleep Bruxism Intensity and Sleep Architecture in Nonapneic Hypertensives: A Prospective, Observational Study.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep bruxism is a common sleep-related behavior characterized as repetitive masticatory muscle activity. Genetic vulnerability to stress and anxiety is considered a basal component in the pathogenesis of bruxism events. Dysfunction of the autonomic nervous system related with an arousal during sleep is considered an underlying cause of the cardiovascular implications of sleep bruxism. Increased cardiovascular risk was previously linked with sleep conditions: for example, obstructive sleep apnea and insomnia, and sleep bruxism. The aim of present systematic review was to evaluate the current arguments on the relationship between sleep bruxism and cardiovascular diseases according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We have reviewed the Embase, PubMed (Medline) and Scopus databases to identify applicable articles (1994-2021). A total of 127 records in English language were identified, then after screening and exclusion of nonrelevant records, 19 full-text articles were evaluated. Finally, we included 12 studies for synthesis. Due to the heterogeneity of the compared studies, only a qualitative comparison and narrative summary were performed. In the majority of studies, increased sympathetic activity was successfully established to escalate heart rate variability, the inflammatory process, oxidative stress, endothelial remodeling and hormonal disturbances, leading to hypertension and other cardiovascular complications.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.