Evidence map›Paper›PMID 34064126›Full record

ReviewAnimals : an open access journal from MDPI2021

Sha Jiang, Fei-Fei Yan, Jia-Ying Hu, Ahmed Mohammed, Heng-Wei Cheng

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. Pooled it
  2. The effects of different doses ofVeterinary and animal science · 2026
    Article
  3. Review
  4. Dietary supplementation with a multi-strainVeterinary and animal science · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Effects of Dietary High-Yield ProteaseAnimals : an open access journal from MDPI · 2025
    Article
  14. Review
  15. Article
  16. Review
  17. Winning the battle of intestinal peace withFrontiers in microbiology · 2025
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Sha JiangJoint International Research Laboratory of Animal Health and Animal Food Safety, College of Veterinary Medicine, Southwest University, Chongqing 400715, China.
Fei-Fei YanAnimal Welfare Institute, College of Animal Science and Technology, Zhejiang A&F University, Hangzhou 311300, China.
Jia-Ying HuDepartment of Animal Science, Purdue University, West Lafayette, IN 47907, USA.
Ahmed MohammedDepartment of Animal and Poultry Behavior and Management, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt.
Heng-Wei ChengUSDA-Agricultural Research Service, Livestock Behavior Research Unit, West Lafayette, IN 47907, USA.
Agricultural Research Service · USAssiut University · EGPurdue University West Lafayette · USSouthwest University · CNZhejiang A & F University · CN

Funding

National Institute of Food and Agriculture 2013-6702-21094
6 · The paper itself

Abstract

The elevation of ambient temperature beyond the thermoneutral zone leads to heat stress, which is a growing health and welfare issue for homeothermic animals aiming to maintain relatively constant reproducibility and survivability. Particularly, global warming over the past decades has resulted in more hot days with more intense, frequent, and long-lasting heat waves, resulting in a global surge in animals suffering from heat stress. Heat stress causes pathophysiological changes in animals, increasing stress sensitivity and immunosuppression, consequently leading to increased intestinal permeability (leaky gut) and related neuroinflammation. Probiotics, as well as prebiotics and synbiotics, have been used to prevent or reduce stress-induced negative effects on physiological and behavioral homeostasis in humans and various animals. The current data indicate dietary supplementation with a

Indexed as

broiler chickengut microbiotaheat stressprobioticskeletal healththe gut–microbiota–brain axiswelfare

Identifiers

PMID34064126
PMCPMC8224346
OpenAlexW3163691716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.