Evidence map›Paper›PMID 34064086›Full record

ArticleMaterials (Basel, Switzerland)2021

Dental Implants with a Calcium Ions-Modified Surface and Platelet Concentrates for the Rehabilitation of Medically Compromised Patients: A Retrospective Study with 5-Year Follow-Up.

Marco Mozzati, Giorgia Gallesio, Giulio Menicucci, Carlo Manzella, Margherita Tumedei, Massimo Del Fabbro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Marco MozzatiPrivate Practitioner, SIOM Oral Surgery and Implantology Center, 10126 Turin, Italy.
Giorgia GallesioPrivate Practitioner, SIOM Oral Surgery and Implantology Center, 10126 Turin, Italy.
Giulio MenicucciProsthodontic Department, School of Dentistry, University of Turin, 10124 Turin, Italy.
Carlo ManzellaProsthodontic Department, School of Dentistry, University of Turin, 10124 Turin, Italy.
Margherita TumedeiDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti, 66100 Chieti, Italy.ORCID 0000-0001-8770-5297
Massimo Del FabbroDepartment of Biomedical, Surgical and Dental Sciences, University of Milano, 20122 Milan, Italy.ORCID 0000-0001-7144-0984
Italian Society of Periodontology and Implantology · ITUniversity of Turin · ITUniversity of Chieti-Pescara · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlatelet concentrates are biological, autologous products obtained from the patient's whole blood, consisting of a supraphysiological concentration of platelets and growth factors, that have proved beneficial in different applications in the medical and dental fields. They are used in several medical and dental applications to enhance tissue healing. Previous evidence shows that platelet concentrates may be beneficial in patients with compromised systemic conditions, in which the healing process is impaired.

aimTo evaluate the 5-year clinical outcome of implant treatment using acid-etched implants with calcium ions-modified surface in association with plasma rich in growth factors, in patients with systemic diseases of a different nature.

methodsCharts of 99 medically compromised patients, who had received a total of 224 dental implants from January 2013 to June 2013, were retrospectively evaluated. Patients were divided into four groups, according to their condition: diabetes (n = 39 patients), osteoporosis (n = 36), lupus erythematosus systemic (n = 5), rheumatoid arthritis (n = 19). The main outcomes were implant survival, marginal bone level (MBL) change and complications throughout follow-up.

resultsMean follow-up was 63.06 ± 1.90 months (range 60.1 to 66.4 months). In total, eight implants failed in 6 diabetic patients and 4 in 3 patients with rheumatoid arthritis. Overall 5-year implant survival was 94.6%. In total, 30 complications occurred in 24 patients, mostly transient, and no severe adverse event occurred. Overall MBL change was 0.45 ± 0.12 mm, with no significant differences among groups.

conclusionsIn the present sample of medically compromised patients, rehabilitation with calcium ions-modified surface implants associated with plasma rich in growth factors proved to be a safe and effective treatment. The satisfactory results achieved after 5-year follow-up are comparable to those historically reported for healthy patients.

Indexed as

calcium-ion modified surfacedental implantsdiabetesgrowth factorslupus erythematosus systemicmedically compromised patientsosteoporosisplasma rich in growth factorsplateletsrheumatoid arthritissystemic diseases

Identifiers

PMID34064086
PMCPMC8196782
OpenAlexW3162453666

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.