Evidence map›Paper›PMID 34064058›Full record

ReviewMedical sciences (Basel, Switzerland)2021

The Mechanisms for the Association of Cancer and Esophageal Dysmotility Disorders.

Francisco Tustumi, Jorge Henrique Bento de Sousa, Nicolas Medeiros Dornelas, Guilherme Maganha Rosa, Milton Steinman, Edno Tales Bianchi

Open access · goldAbstract readReview
In one paragraph

Review in Medical sciences (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Late Onset of Pseudoachalasia in Anti-Hu-Associated Syndrome.Case reports in gastrointestinal medicine · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Microbial Dysbiosis in Achalasia: Insights on How to Prevent Cancer.Journal of neurogastroenterology and motility · 2022
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Francisco TustumiHospital Israelita Albert Einstein, Sao Paulo 05652-900, Brazil.ORCID 0000-0001-6695-0496
Jorge Henrique Bento de SousaHospital Israelita Albert Einstein, Sao Paulo 05652-900, Brazil.
Nicolas Medeiros DornelasHospital Israelita Albert Einstein, Sao Paulo 05652-900, Brazil.ORCID 0000-0002-8199-0397
Guilherme Maganha RosaHospital Israelita Albert Einstein, Sao Paulo 05652-900, Brazil.
Milton SteinmanHospital Israelita Albert Einstein, Sao Paulo 05652-900, Brazil.
Edno Tales BianchiHospital Israelita Albert Einstein, Sao Paulo 05652-900, Brazil.
Hospital Israelita Albert Einstein · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAchalasia and other esophageal dysmotility disorders mimicking achalasia can be associated with cancer. This study aimed to review the main mechanisms for which cancer may develop in esophageal dysmotility disorder patients.

methodsA narrative review was performed.

resultsThe mechanism for developing squamous cell carcinoma and adenocarcinoma are discussed. Besides, achalasia-like syndromes related to familial KIT-gene mutation and pseudoachalasia are discussed.

conclusionsKnowing the main mechanism for which achalasia can be related to cancer is essential for clinicians to conduct the proper investigation, surveillance, and treatment.

Indexed as

AdenocarcinomaCarcinoma, Squamous CellEsophageal AchalasiaEsophageal Motility DisordersEsophageal NeoplasmsHumansachalasiacarcinomaesophagusneoplasmsquamous cell carcinoma

Identifiers

PMID34064058
PMCPMC8163009
OpenAlexW3164521734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.