Evidence map›Paper›PMID 34064028›Full record

ArticleVaccines2021

Prevalence of Anti-SARS-CoV-2 Antibodies in Poznań, Poland, after the First Wave of the COVID-19 Pandemic.

Dagny Lorent, Rafal Nowak, Carolina Roxo, Elzbieta Lenartowicz, Aleksandra Makarewicz, Bartosz Zaremba, Szymon Nowak, Lukasz Kuszel, Jerzy Stefaniak, Ryszard Kierzek and 1 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Dagny LorentInstitute of Bioorganic Chemistry Polish Academy of Sciences, 61-704 Poznan, Poland.ORCID 0000-0001-8276-3746
Rafal NowakInstitute of Bioorganic Chemistry Polish Academy of Sciences, 61-704 Poznan, Poland.
Carolina RoxoInstitute of Bioorganic Chemistry Polish Academy of Sciences, 61-704 Poznan, Poland.ORCID 0000-0001-6563-4192
Elzbieta LenartowiczInstitute of Bioorganic Chemistry Polish Academy of Sciences, 61-704 Poznan, Poland.ORCID 0000-0002-3596-4470
Aleksandra MakarewiczInstitute of Bioorganic Chemistry Polish Academy of Sciences, 61-704 Poznan, Poland.ORCID 0000-0001-9310-9643
Bartosz ZarembaInstitute of Bioorganic Chemistry Polish Academy of Sciences, 61-704 Poznan, Poland.
Szymon NowakDepartment and Clinic of Tropical and Parasitic Diseases, Poznan University of Medical Sciences, 60-355 Poznan, Poland.ORCID 0000-0001-9404-5100
Lukasz KuszelDepartment of Medical Genetics, Poznan University of Medical Sciences, 60-355 Poznan, Poland.ORCID 0000-0002-7783-6370
Jerzy StefaniakDepartment and Clinic of Tropical and Parasitic Diseases, Poznan University of Medical Sciences, 60-355 Poznan, Poland.
Ryszard KierzekInstitute of Bioorganic Chemistry Polish Academy of Sciences, 61-704 Poznan, Poland.
Pawel ZmoraInstitute of Bioorganic Chemistry Polish Academy of Sciences, 61-704 Poznan, Poland.ORCID 0000-0002-2012-7223
Institute of Bioorganic Chemistry, Polish Academy of Sciences · PLPoznan University of Medical Sciences · PL

Funding

Narodowe Centrum Nauki UMO-2020/01/0/NZ6/00152
6 · The paper itself

Abstract

In comparison to other European countries, during the first months of the COVID-19 pandemic, Poland reported a relatively low number of confirmed cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. To estimate the scale of the pandemic in Poland, a serosurvey of antibodies against SARS-CoV-2 was performed after the first wave of COVID-19 in Europe (March-May 2020). Within this study, we collected samples from 28 July to 24 September 2020 and, based on the ELISA results, we found that 1.67% (25/1500, 95% CI 1.13-2.45) of the Poznan (Poland) metropolitan area's population had antibodies against SARS-CoV-2 after the first wave of COVID-19. However, the presence of anti-SARS-CoV-2 IgG antibodies was confirmed with immunoblotting in 56% (14/25) samples, which finally resulted in a decrease in seroprevalence, i.e., 0.93% (14/1500, 95% CI 0.56-1.56). The positive anti-SARS-CoV-2 IgG results were associated with age, occupation involving constant contact with people, travelling abroad, non-compliance with epidemiological recommendations and direct contact with the novel coronavirus. Our findings confirm the low SARS-CoV-2 incidence in Poland and imply that the population had little herd immunity heading into the second and third wave of the pandemic, and therefore, that herd immunity contributed little to preventing the high numbers of SARS-CoV-2 infections and COVID-19-related deaths in Poland during these subsequent waves.

Indexed as

antibodiesCOVID-19pandemicPolandSARS-CoV-2seroprevalence

Identifiers

PMID34064028
PMCPMC8223993
OpenAlexW3165495195

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.