Evidence map›Paper›PMID 34063999›Full record

ArticleCells2021

Expression of Immuno-Oncologic Biomarkers Is Enriched in Colorectal Cancers and Other Solid Tumors Harboring the A59T Variant of

Emil Lou, Joanne Xiu, Yasmine Baca, Andrew C Nelson, Benjamin A Weinberg, Muhammad Shaalan Beg, Mohamed E Salem, Heinz-Josef Lenz, Philip Philip, Wafik S El-Deiry and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Emil LouDivision of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-1607-1386
Joanne XiuCaris Life Sciences, Phoenix, AZ 85040, USA.
Yasmine BacaCaris Life Sciences, Phoenix, AZ 85040, USA.ORCID 0000-0003-2130-0611
Andrew C NelsonLaboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-4741-0010
Benjamin A WeinbergRuesch Center for the Cure of Gastrointestinal Cancers, Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA.
Muhammad Shaalan BegSimmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Mohamed E SalemDepartment of Medical Oncology, Levine Cancer Institute, North Carolina, NC 28204, USA.
Heinz-Josef LenzMedicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.
Philip PhilipDepartment of Oncology, School of Medicine, Wayne State University, Detroit, MI 48202, USA.
Wafik S El-DeiryDivision of Hematology/Oncology, Lifespan Cancer Institute, Department of Pathology & Laboratory Medicine, The Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
W Michael KornCaris Life Sciences, Phoenix, AZ 85040, USA.
Caris Life Sciences (United States) · USUniversity of Minnesota · USBrown University · USLevine Cancer Institute · USThe University of Texas Southwestern Medical Center · USUniversity of Southern California · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular heterogeneity of

Indexed as

Biomarkers, TumorColorectal NeoplasmsHumansProto-Oncogene Proteins p21(ras)Biomarkers, TumorKRAS protein, humanProto-Oncogene Proteins p21(ras)A59Tcolon cancercolorectal cancerimmuno-oncologyKRASmolecular oncologyoncogenepredictive biomarkers

Identifiers

PMID34063999
PMCPMC8224072
OpenAlexW3161152801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.