Evidence map›Paper›PMID 34063984›Full record

ArticleMarine drugs2021

Total Synthesis and Anti-Inflammatory Bioactivity of (-)-Majusculoic Acid and Its Derivatives.

Hong-Xiu Xiao, Qing-Xiang Yan, Zhi-Hui He, Zheng-Biao Zou, Qing-Qing Le, Ting-Ting Chen, Bing Cai, Xian-Wen Yang, Su-Lan Luo

Abstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Synthetic Process Development of (Organic process research & development · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hong-Xiu XiaoKey Laboratory of Tropical Biological Resources of Ministry of Education, Hainan University, Haikou 570228, China.
Qing-Xiang YanKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen 361005, China.
Zhi-Hui HeKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen 361005, China.
Zheng-Biao ZouKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen 361005, China.
Qing-Qing LeKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen 361005, China.
Ting-Ting ChenKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen 361005, China.
Bing CaiKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen 361005, China.
Xian-Wen YangKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen 361005, China.ORCID 0000-0002-4967-0844
Su-Lan LuoKey Laboratory of Tropical Biological Resources of Ministry of Education, Hainan University, Haikou 570228, China.ORCID 0000-0002-9358-5970

Funding

the National Natural Science Foundation of China 21877022
6 · The paper itself

Abstract

The first total synthesis of marine natural product, (-)-majusculoic acid (

Indexed as

AnimalsAnti-Inflammatory AgentsCell ProliferationFatty Acids, UnsaturatedHydrocarbons, BrominatedLipopolysaccharidesMacrophagesMiceNitric OxideRAW 264.7 CellsStructure-Activity RelationshipAnti-Inflammatory AgentsFatty Acids, UnsaturatedHydrocarbons, BrominatedLipopolysaccharidesmajusculoic acidNitric Oxideanti-inflammationCCK-8LPS(−)-majusculoic acidmarine natural products

Identifiers

PMID34063984
PMCPMC8223986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.