Evidence map›Paper›PMID 34063960›Full record

ArticleLife (Basel, Switzerland)2021

Antiretroviral Therapy Improves Acquired Immunodeficiency Syndrome with Systemic Lupus Erythematosus.

Akinori Okada, Yuji Nozaki, Shinya Rai, Koji Kinoshita, Masanori Funauchi, Itaru Matsumura

Open access · goldAbstract readCase Reports
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. HIV-Associated Systemic Sclerosis: Literature Review and a Rare Case Report.International journal of environmental research and public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Akinori OkadaDepartment of Hematology and Rheumatology, Faculty of Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan.ORCID 0000-0002-2764-176X
Yuji NozakiDepartment of Hematology and Rheumatology, Faculty of Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan.ORCID 0000-0003-2810-1519
Shinya RaiDepartment of Hematology and Rheumatology, Faculty of Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan.ORCID 0000-0003-3929-9751
Koji KinoshitaDepartment of Hematology and Rheumatology, Faculty of Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan.
Masanori FunauchiDepartment of Hematology and Rheumatology, Faculty of Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan.
Itaru MatsumuraDepartment of Hematology and Rheumatology, Faculty of Medicine, Kindai University, Osaka-Sayama, Osaka 589-8511, Japan.
Kindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 35-year-old male was referred to our hospital with dysesthesia of the lower extremities that had begun six months earlier. A blood test revealed the presence of various antibodies, suggesting a collagen-related peripheral neuropathy. However, a history of repeated shingles and sex with males was noted, and the patient was tested for and diagnosed with human immunodeficiency virus (HIV) infection. Based on the manifestations and laboratory data, including the results of immunological and urinary tests, he was further diagnosed with concomitant systemic lupus erythematosus (SLE). The activity of SLE improved with antiretroviral therapy. There is currently no established treatment for AIDS complicated with SLE. Indeed, because HIV treatment involves the activation of immune function and SLE treatment involves immunosuppression, any treatments for the two conditions would be in conflict. It is thus necessary to select a treatment strategy based on the condition of the individual patient. In addition, because HIV infection is relatively rare in Japan compared to other countries, rheumatologists in Japan must keep HIV infection in mind as a differential diagnosis for autoimmune diseases.

Indexed as

acquired immunodeficiency syndromeantiretroviral therapyautoimmune diseasehuman immunodeficiency virussystemic lupus erythematosus

Identifiers

PMID34063960
PMCPMC8223983
OpenAlexW3164135665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.