Evidence map›Paper›PMID 34063886›Full record

ArticleCancers2021

Case-Control Analysis of the Impact of Anemia on Quality of Life in Patients with Cancer: A Qca Study Analysis.

Maria Barca-Hernando, Andres J Muñoz-Martin, Eduardo Rios-Herranz, Ignacio Garcia-Escobar, Carmen Beato, Carme Font, Estefania Oncala-Sibajas, Alfonso Revuelta-Rodriguez, Maria Carmen Areses, Victor Rivas-Jimenez and 18 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Development and validation of a machine learning model to predict moderate-to-severe cancer-related fatigue in breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 12 institutions in 1 country.

Maria Barca-HernandoMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Andres J Muñoz-MartinMedical Oncology Department, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.
Eduardo Rios-HerranzHematology and Hemotherapy Department, Hospital Universitario Virgen de Valme, 41701 Sevilla, Spain.
Ignacio Garcia-EscobarMedical Oncology Department, Hospital Universitario Virgen de las Nieves, 18014 Granada, Spain.
Carmen BeatoMedical Oncology Department, Hospital Virgen de la Macarena, 41009 Sevilla, Spain.
Carme FontMedical Oncology Department, DIBAPS/Translational Genomics and Targeted Therapeutics in Solid Tumors, Hospital Clínic, 08036 Barcelona, Spain.
Estefania Oncala-SibajasEmergency Department, Hospital Virgen Macarena, 41009 Sevilla, Spain.
Alfonso Revuelta-RodriguezMedical Oncology Department, Hospital Universitario Central de Asturias, 33611 Oviedo, Spain.
Maria Carmen AresesMedical Oncology Department, Hospital de Orense, 32616 Orense, Spain.
Victor Rivas-JimenezMedical Oncology Department, Hospital de Jerez de la Frontera, 11407 Cádiz, Spain.
Aitor Ballaz-QuincocesRespiratory Department, Hospital de Galdakao-Usansolo, 48960 Bizkaia, Spain.
Maria Angeles Moreno-SantosMedical Oncology Department, Hospital Universitario Puerto Real, 11510 Cádiz, Spain.
Juan-Bosco Lopez-SaezInternal Medicine Unit, Hospital Universitario, Puerto Real, 11510 Cádiz, Spain.
Iria Gallego-GallegoMedical Oncology Department, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.
Teresa Elias-HernandezMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Maria Isabel Asensio-CruzMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Leyre Chasco-EguilazRespiratory Department, Hospital de Galdakao-Usansolo, 48960 Bizkaia, Spain.
Gonzalo Garcia-GonzalezMedical Oncology Department, Hospital General Universitario Gregorio Marañón, 28009 Madrid, Spain.
Purificacion Estevez-GarciaMedical Oncology Department, Hospital Virgen del Rocio, 41013 Sevilla, Spain.
Lucia Marin-BarreraMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Remedios Otero-CandeleraMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Sergio Lopez-RuzMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Jorge Lima-AlvarezRespiratory Department, Hospital Universitario Virgen de Valme, 41701 Sevilla, Spain.
Jose Maria Sanchez-DiazMedical Surgical Unit of Respiratory Diseases, Pharmacy, Respiratory Department, Hospital Virgen del Rocio, 41013 Sevilla, Spain.
Macarena Real-DominguezDepartment of Preventive Medicine and Public Health, Universidad de Málaga, 29071 Málaga, Spain.
Maria Carmen Borrego-DelgadoMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Samira Marin-RomeroMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Luis Jara-PalomaresMedical Surgical Unit of Respiratory Diseases, Respiratory Department, Hospital Virgen del Rocio, CIBERES, 41013 Sevilla, Spain.
Hospital Universitario Virgen del Rocío · ESCentro de Investigación Biomédica en Red · ESHospital General Universitario Gregorio Marañón · ESHospital de Galdakao · ESHospital Universitario de Valme · ESHospital Universitario Puerto Real · ESHospital Universitario Virgen Macarena · ESComplejo Hospitalario de Ourense · ESHospital Jerez Puerta del Sur · ESHospital Universitario Central de Asturias · ESHospital Universitario Virgen de las Nieves · ESUniversidad de Málaga · ES

Funding

Leo Pharma 6/2013Neumosur 9/2014
6 · The paper itself

Abstract

Anemia is a common condition in cancer patients and is associated with a wide variety of symptoms that impair quality of life (QoL). However, exactly how anemia affects QoL in cancer patients is unclear because of the inconsistencies in its definition in previous reports. We aimed to examine the clinical impact of anemia on the QoL of cancer patients using specific questionnaires. We performed a post-hoc analysis of a multicenter, prospective, case-control study. We included patients with cancer with (cases) or without (controls) anemia. Participants completed the European Organization for Research and Treatment of Cancer Quality of Life questionnaire version 3.0 (EORTC QLQ-C30) and Euro QoL 5-dimension 3-level (EQ-5D-3L) questionnaire. Statistically significant and clinically relevant differences in the global health status were examined. From 2015 to 2018, 365 patients were included (90 cases and 275 controls). We found minimally important differences in global health status according to the EORTC QLQ-C30 questionnaire (case vs. controls: 45.6 vs. 58%, respectively; mean difference: -12.4,

Indexed as

anaemianeoplasmquality of life

Identifiers

PMID34063886
PMCPMC8196564
OpenAlexW3165516468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.