Evidence map›Paper›PMID 34063846›Full record

ArticleAntibiotics (Basel, Switzerland)2021

New Quinone Antibiotics against Methicillin-Resistant

Javier Campanini-Salinas, Juan Andrades-Lagos, Nicolás Hinojosa, Fabián Moreno, Pedro Alarcón, Gerardo González-Rocha, Ian E Burbulis, David Vásquez-Velásquez

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Javier Campanini-SalinasDrug Development Laboratory, Faculty of Chemical and Pharmaceutical, Sciences, Universidad de Chile, Sergio Livingstone 1007, Santiago 8380492, Chile.ORCID 0000-0002-7358-409X
Juan Andrades-LagosDrug Development Laboratory, Faculty of Chemical and Pharmaceutical, Sciences, Universidad de Chile, Sergio Livingstone 1007, Santiago 8380492, Chile.
Nicolás HinojosaDrug Development Laboratory, Faculty of Chemical and Pharmaceutical, Sciences, Universidad de Chile, Sergio Livingstone 1007, Santiago 8380492, Chile.
Fabián MorenoDrug Development Laboratory, Faculty of Chemical and Pharmaceutical, Sciences, Universidad de Chile, Sergio Livingstone 1007, Santiago 8380492, Chile.
Pedro AlarcónAgents of Bacterial Meningitis Laboratory, Instituto de Salud Pública de Chile, Santiago 7780050, Chile.
Gerardo González-RochaLaboratorio de Investigación en Agentes Antibacterianos (LIAA), Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción 4070386, Chile.ORCID 0000-0003-2351-1236
Ian E BurbulisCentro de Investigación Biomédica, Facultad de Medicina y Ciencias, Universidad San Sebastián, Sede de la Patagonia, Lago Panguipulli 1390, Puerto Montt 5501842, Chile.
David Vásquez-VelásquezDrug Development Laboratory, Faculty of Chemical and Pharmaceutical, Sciences, Universidad de Chile, Sergio Livingstone 1007, Santiago 8380492, Chile.ORCID 0000-0003-0635-4857

Funding

LAMPoles for Dengue DiagnosisR21AI111072 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GRAB, DENNIS JOHN · 2015 to 2016
$452k
NIAID NIH HHS R21 AI111072
6 · The paper itself

Abstract

There is an urgent need for the development of new antibiotics. Here, we describe the inhibitory activity of new quinone compounds against methicillin-resistant

Indexed as

drug discoverymethicillin-resistant S. aureus (MRSA)quinone-antibiotics

Identifiers

PMID34063846
PMCPMC8224091

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.