Evidence map›Paper›PMID 34063824›Full record

ArticleJournal of personalized medicine2021

Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection.

Ljiljana Marcic, Marino Marcic, Sanja Lovric Kojundzic, Barbara Marcic, Vesna Capkun, Katarina Vukojevic

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ljiljana MarcicDepartment of Radiology, Polyclinic Medicol, Šoltanska 1, 21000 Split, Croatia.
Marino MarcicDepartment of Neurology, University Hospital Center Split, Spinčićeva 1, 21000 Split, Croatia.
Sanja Lovric KojundzicDepartment of Radiology, University Hospital Center Split, Spinčićeva 1, 21000 Split, Croatia.
Barbara MarcicDepartment of Medical Genetics, University of Mostar School of Medicine, Petra Krešimira IV bb, 88000 Mostar, Bosnia and Herzegovina.
Vesna CapkunDepartment of Anatomy, Histology and Embryology, University of Split School of Medicine, Šoltanska 2, 21000 Split, Croatia.
Katarina VukojevicDepartment of Medical Genetics, University of Mostar School of Medicine, Petra Krešimira IV bb, 88000 Mostar, Bosnia and Herzegovina.ORCID 0000-0003-2182-2890
University of Split · HRUniversity of Mostar · BAKlinički Bolnički Centar Split · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From the beginning of SARS-CoV-2 virus pandemic, it was clear that respiratory symptoms are often accompanied with neurological symptoms. Neurological manifestations can occur even after mild forms of respiratory disease, and neurological symptoms are very often associated with worsening of the patient's condition. The aim of this study was to show abnormal brain neuroimaging findings evaluated by MRI in patients after SARS-CoV-2 infection and neurological symptoms. Methods: Sixteen patients after mild forms of SARS-CoV-2 infection, twenty-three patients after moderate forms of SARS-CoV-2 infection as well as sixteen healthy participants in the control group underwent MRI 3T brain scan. All subjects in the SARS-CoV-2 group had small, punctuate, strategically located and newly formed hyperintense lesions on T2 and FLAIR sequences. New lesions were formed more often in the bilateral frontal subcortical and bilateral periventricular, correlated with the severity of the clinical picture. These changes indicate an example of silent cerebrovascular disease related to SARS-CoV-2 and once again emphasize the neurotropism of the virus.

Indexed as

brainMRIneurological symptomsSARS-CoV-2

Identifiers

PMID34063824
PMCPMC8224015
OpenAlexW3161570205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.