Carbonized Lysine-Nanogels Protect against Infectious Bronchitis Virus.

Ding-Li Chou, Ju-Yi Mao, Anisha Anand, Han-Jia Lin, John Han-You Lin, Ching-Ping Tseng, Chih-Ching Huang, Hsian-Yu Wang

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it

0cells of the map it votes in

3citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

An Overview of the Potential of Food-Based Carbon Dots for Biomedical Applications.International journal of molecular sciences · 2023
Review
Molecular and Macromolecular Interactions of Carbon-Based Nanostructures.International journal of molecular sciences · 2022
Article
Novel and Alternative Therapeutic Strategies for Controlling Avian Viral Infectious Diseases: Focus on Infectious Bronchitis and Avian Influenza.Frontiers in veterinary science · 2022
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ding-Li ChouDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.

Ju-Yi MaoDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung 20224, Taiwan.ORCID 0000-0002-3008-5717

Anisha AnandDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung 20224, Taiwan.

Han-Jia LinDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung 20224, Taiwan.ORCID 0000-0002-4929-6573

John Han-You LinSchool of Veterinary Medicine, National Taiwan University, Taipei 10617, Taiwan.

Ching-Ping TsengDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.

Chih-Ching HuangDepartment of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung 20224, Taiwan.ORCID 0000-0002-0363-1129

Hsian-Yu WangGraduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 91201, Taiwan.ORCID 0000-0002-7060-3005

Funding

Ministry of Science and Technology, Taiwan 107-2113-M-019-004-MY3Ministry of Science and Technology, Taiwan 109-2313-B-019-005Ministry of Science and Technology, Taiwan 109-2313-B-020-005Ministry of Science and Technology, Taiwan 109-2622-B-019-007

6 · The paper itself

Abstract

In this study, we demonstrate the synthesis of carbonized nanogels (CNGs) from an amino acid (lysine hydrochloride) using a simple pyrolysis method, resulting in effective viral inhibition properties against infectious bronchitis virus (IBV). The viral inhibition of CNGs was studied using both in vitro (bovine ephemeral fever virus (BEFV) and pseudorabies virus (PRV)) and in ovo (IBV) models, which indicated that the CNGs were able to prevent virus attachment on the cell membrane and penetration into the cell. A very low concentration of 30 μg mL

Indexed as

AnimalsAntiviral AgentsCell LineChickensChlorocebus aethiopsCoronavirus InfectionsCricetinaeEphemeral Fever Virus, BovineFemaleHerpesvirus 1, SuidInfectious bronchitis virusLysineNanogelsPoultry DiseasesProtective AgentsRatsAntiviral AgentsLysineNanogelsProtective Agentsantiviral agentscarbonizationinfectious bronchitis viruslysinenanogels

Identifiers

PMID34063782

DOI10.3390/ijms22115415

PMCPMC8196573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.