Evidence map›Paper›PMID 34063713›Full record

ReviewMolecules (Basel, Switzerland)2021

Recent Developments in Chitosan-Based Micro/Nanofibers for Sustainable Food Packaging, Smart Textiles, Cosmeceuticals, and Biomedical Applications.

Nguyen D Tien, Ståle Petter Lyngstadaas, João F Mano, Jonathan James Blaker, Håvard J Haugen

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Nanomaterials (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Biomimetic Scaffolds for Tendon Tissue Regeneration.Biomimetics (Basel, Switzerland) · 2023
    Review
  11. Review
  12. Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Nguyen D TienDepartment of Biomaterials, Institute of Clinical Dentistry, University of Oslo, 0317 Oslo, Norway.ORCID 0000-0002-0378-8492
Ståle Petter LyngstadaasDepartment of Biomaterials, Institute of Clinical Dentistry, University of Oslo, 0317 Oslo, Norway.
João F ManoCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-2342-3765
Jonathan James BlakerDepartment of Biomaterials, Institute of Clinical Dentistry, University of Oslo, 0317 Oslo, Norway.ORCID 0000-0003-1112-8619
Håvard J HaugenDepartment of Biomaterials, Institute of Clinical Dentistry, University of Oslo, 0317 Oslo, Norway.ORCID 0000-0002-6690-7233
University of Oslo · NOUniversity of Aveiro · PT

Funding

Fundación Española para la Ciencia y la Tecnología UIDB/50011/2020Fundación Española para la Ciencia y la Tecnología UIDP/50011/2020Norges Forskningsråd 287991
6 · The paper itself

Abstract

Chitosan has many useful intrinsic properties (e.g., non-toxicity, antibacterial properties, and biodegradability) and can be processed into high-surface-area nanofiber constructs for a broad range of sustainable research and commercial applications. These nanofibers can be further functionalized with bioactive agents. In the food industry, for example, edible films can be formed from chitosan-based composite fibers filled with nanoparticles, exhibiting excellent antioxidant and antimicrobial properties for a variety of products. Processing 'pure' chitosan into nanofibers can be challenging due to its cationic nature and high crystallinity; therefore, chitosan is often modified or blended with other materials to improve its processability and tailor its performance to specific needs. Chitosan can be blended with a variety of natural and synthetic polymers and processed into fibers while maintaining many of its intrinsic properties that are important for textile, cosmeceutical, and biomedical applications. The abundance of amine groups in the chemical structure of chitosan allows for facile modification (e.g., into soluble derivatives) and the binding of negatively charged domains. In particular, high-surface-area chitosan nanofibers are effective in binding negatively charged biomolecules. Recent developments of chitosan-based nanofibers with biological activities for various applications in biomedical, food packaging, and textiles are discussed herein.

Indexed as

Food PackagingTextilesAminesAnimalsAnti-Bacterial AgentsAnti-Infective AgentsAntioxidantsChitosanCosmeceuticalsCrystallizationEdible FilmsHumansNanofibersNanoparticlesPolymersRegenerationAminesAnti-Bacterial AgentsAnti-Infective AgentsAntioxidantsChitosanCosmeceuticalsPolymersadvanced textilesbiofunctionalized materialschitosan nanofibersdermal regenerationskin graft substitutesustainable food packagingwound care

Identifiers

PMID34063713
PMCPMC8125268
OpenAlexW3158421247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.