Evidence map›Paper›PMID 34063592›Full record

ArticleHealthcare (Basel, Switzerland)2021

Feasibility of a Portable Electronic Nose for Detection of Oral Squamous Cell Carcinoma in Sudan.

Nazar Mohamed, Rens van de Goor, Mariam El-Sheikh, Osman Elrayah, Tarig Osman, Elisabeth Sivy Nginamau, Anne Christine Johannessen, Ahmed Suleiman, Daniela Elena Costea, Kenneth W Kross

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nazar MohamedCenter for Cancer Biomarkers (CCBIO) and Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, P.O. Box 7800, 5020 Bergen, Norway.
Rens van de GoorDepartment of Otolaryngology-Head and Neck Surgery, Bernhoven Hospital, P.O. Box 707, 5400 AS Uden, The Netherlands.
Mariam El-SheikhDepartment of Oral and Maxillofacial Surgery and Department of Basic Sciences, University of Khartoum, P.O. Box 321, 11111 Khartoum, Sudan.
Osman ElrayahDepartment of Oral and Maxillofacial Surgery and Department of Basic Sciences, University of Khartoum, P.O. Box 321, 11111 Khartoum, Sudan.
Tarig OsmanCenter for Cancer Biomarkers (CCBIO) and Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, P.O. Box 7800, 5020 Bergen, Norway.
Elisabeth Sivy NginamauCenter for Cancer Biomarkers (CCBIO) and Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, P.O. Box 7800, 5020 Bergen, Norway.
Anne Christine JohannessenCenter for Cancer Biomarkers (CCBIO) and Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, P.O. Box 7800, 5020 Bergen, Norway.
Ahmed SuleimanDepartment of Oral and Maxillofacial Surgery and Department of Basic Sciences, University of Khartoum, P.O. Box 321, 11111 Khartoum, Sudan.
Daniela Elena CosteaCenter for Cancer Biomarkers (CCBIO) and Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, P.O. Box 7800, 5020 Bergen, Norway.ORCID 0000-0001-7673-0358
Kenneth W KrossDepartment of Otolaryngology-Head and Neck Surgery, Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX Maastricht, The Netherlands.

Funding

Helse Vest Regionalt Helseføretak 912260/2019Norges Forskningsråd 22325
6 · The paper itself

Abstract

backgroundOral squamous cell carcinoma (OSCC) is increasing at an alarming rate particularly in low-income countries. This urges for research into noninvasive, user-friendly diagnostic tools that can be used in limited-resource settings. This study aims to test and validate the feasibility of e-nose technology for detecting OSCC in the limited-resource settings of the Sudanese population.

methodsTwo e-nose devices (Aeonose™, eNose Company, Zutphen, The Netherlands) were used to collect breath samples from OSCC (

resultsA diagnostic accuracy of 81% was observed, with 88% sensitivity and 71% specificity.

conclusionsThis study demonstrates that e-nose is an efficient tool for OSCC detection in limited-resource settings, where it offers a valuable cost-effective strategy to tackle the burden posed by OSCC.

Indexed as

cancerdiagnosiselectronic noseoralscreeningtoombak

Identifiers

PMID34063592
PMCPMC8147635

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.