Evidence map›Paper›PMID 34063398›Full record

ArticleNutrients2021

A Combined Analysis of Gut and Skin Microbiota in Infants with Food Allergy and Atopic Dermatitis: A Pilot Study.

Ewa Łoś-Rycharska, Marcin Gołębiewski, Marcin Sikora, Tomasz Grzybowski, Marta Gorzkiewicz, Maria Popielarz, Julia Gawryjołek, Aneta Krogulska

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Review
  7. Article
  8. Article
  9. Review
  10. Effect of herbal medicineFrontiers in pharmacology · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Gut microbiome is associated with asthma and race in children with food allergy.The Journal of allergy and clinical immunology · 2023
    Article
  18. Article
  19. The methylation profile ofFrontiers in immunology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ewa Łoś-RycharskaDepartment of Pediatrics, Allergology and Gastroenterology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.
Marcin GołębiewskiDepartment of Plant Physiology and Biotechnology, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.ORCID 0000-0003-2039-8733
Marcin SikoraInterdisciplinary Centre of Modern Technologies, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.
Tomasz GrzybowskiDepartment of Forensic Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.
Marta GorzkiewiczDepartment of Forensic Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.
Maria PopielarzDepartment of Pediatrics, Allergology and Gastroenterology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.ORCID 0000-0002-5247-8589
Julia GawryjołekDepartment of Pediatrics, Allergology and Gastroenterology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.
Aneta KrogulskaDepartment of Pediatrics, Allergology and Gastroenterology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, 87-100 Toruń, Poland.
Nicolaus Copernicus University · PL

Funding

National Science Centre Poland 2017/25/B/NZ5/00141
6 · The paper itself

Abstract

The gut microbiota in patients with food allergy, and the skin microbiota in atopic dermatitis patients differ from those of healthy people. We hypothesize that relationships may exist between gut and skin microbiota in patients with allergies. The aim of this study was to determine the possible relationship between gut and skin microbiota in patients with allergies, hence simultaneous analysis of the two compartments of microbiota was performed in infants with and without allergic symptoms. Fifty-nine infants with food allergy and/or atopic dermatitis and 28 healthy children were enrolled in the study. The skin and gut microbiota were evaluated using 16S rRNA gene amplicon sequencing. No significant differences in the α-diversity of dermal or fecal microbiota were observed between allergic and non-allergic infants; however, a significant relationship was found between bacterial community structure and allergy phenotypes, especially in the fecal samples. Certain clinical conditions were associated with characteristic bacterial taxa in the skin and gut microbiota. Positive correlations were found between skin and fecal samples in the abundance of

Indexed as

Gastrointestinal MicrobiomeMicrobiotaBacteriaDermatitis, AtopicDysbiosisFecesFemaleFood HypersensitivityHumansImmunoglobulin EInfantMaleMetagenomePilot ProjectsRNA, Ribosomal, 16SSkinImmunoglobulin ERNA, Ribosomal, 16S16S rRNA sequencingatopic dermatitisdysbiosisfood allergygutinfantsmicrobiotaskin

Identifiers

PMID34063398
PMCPMC8156695
OpenAlexW3162566203

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.