Evidence map›Paper›PMID 34063276›Full record

Trial reportBiomolecules2021

Serological Biomarkers and Diversion Colitis: Changes after Stimulation with Probiotics.

Ángela Rodríguez-Padilla, Germán Morales-Martín, Rocío Pérez-Quintero, Juan Gómez-Salgado, Carlos Ruiz-Frutos

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ángela Rodríguez-PadillaDepartment of General Surgery, Infanta Elena University Clinical Hospital, 21080 Huelva, Spain.
Germán Morales-MartínDepartment of General Surgery, Infanta Elena University Clinical Hospital, 21080 Huelva, Spain.
Rocío Pérez-QuinteroDepartment of General Surgery, Juan Ramón Jiménez University Clinical Hospital, 21005 Huelva, Spain.
Juan Gómez-SalgadoDepartment of Sociology, Social Work and Public Health, Faculty of Labour Sciences, University of Huelva, 21007 Huelva, Spain.ORCID 0000-0001-9053-7730
Carlos Ruiz-FrutosDepartment of Sociology, Social Work and Public Health, Faculty of Labour Sciences, University of Huelva, 21007 Huelva, Spain.ORCID 0000-0003-3715-1382
Hospital Universitario Infanta Leonor · ESUniversidad de Especialidades Espíritu Santo · ECHospital Juan Ramón Jiménez · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diversion colitis is a non-specific inflammation of a defunctionalised segment of the colon after a temporary stoma has been performed. This inflammation is associated with an alteration of certain inflammatory serum markers. The aims of this study were, firstly, to evaluate the modification of inflammatory biomarkers after stimulation with probiotics prior to closure of the protective ileostomy. Secondly, to identify if a relationship could be established between the severity of diversion colitis and the alteration of inflammatory biomarkers in the blood. A prospective, randomized, double-blind, controlled study was conducted. Patients who underwent surgery for colorectal carcinoma with protective ileostomy between January 2017 and December 2018 were included, pending reconstructive surgery and with diversion colitis as diagnosis. The sample was randomly divided into a group stimulated with probiotics (SG) (

Indexed as

AdultAgedAged, 80 and overBiomarkersColorectal NeoplasmsC-Reactive ProteinDouble-Blind MethodFemaleHumansIleostomyLymphocyte CountMaleMiddle AgedMonocytesNeutrophilsPlatelet CountBiomarkersC-Reactive ProteinTransferrinC-reactive proteindiversion colitisefferent loop stimulationGlasgow Pronostic Scoreinflammatory bowel diseaseprobioticsserological biomarkers

Identifiers

PMID34063276
PMCPMC8147466
OpenAlexW3158483228

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.