Evidence map›Paper›PMID 34063148›Full record

ArticleMolecules (Basel, Switzerland)2021

Protective Role of Vanillic Acid against Diethylnitrosamine- and 1,2-Dimethylhydrazine-Induced Hepatocarcinogenesis in Rats.

Charatda Punvittayagul, Arpamas Chariyakornkul, Kanokwan Jarukamjorn, Rawiwan Wongpoomchai

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
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  11. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Curative Potential of Substances with Bioactive Properties to Alleviate Cd Toxicity: A Review.International journal of environmental research and public health · 2022
    Review
  16. Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Charatda PunvittayagulResearch Affairs, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai 50100, Thailand.ORCID 0000-0002-1637-6884
Arpamas ChariyakornkulDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-0463-2289
Kanokwan JarukamjornResearch Group for Pharmaceutical Activities of Natural Products Using Pharmaceutical Biotechnology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Rawiwan WongpoomchaiDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-6999-8436
Chiang Mai University · THKhon Kaen University · TH

Funding

The Thailand Research Fund (TRF) TRG6080006
6 · The paper itself

Abstract

This study aimed to evaluate the cancer chemopreventive activity of vanillic acid (VA) in diethylnitrosamine- and 1,2-dimethylhydrazine-induced liver and colon carcinogenesis in rats. VA did not induce the formation of hepatic glutathione

Indexed as

1,2-DimethylhydrazineAlanine TransaminaseAnimalsApoptosisAspartate AminotransferasesCarcinogenesisCell ProliferationDiethylnitrosamineGene Expression Regulation, NeoplasticLiver NeoplasmsMaleOrgan SizeProtective AgentsRatsRats, WistarVanillic Acid1,2-DimethylhydrazineAlanine TransaminaseAspartate AminotransferasesDiethylnitrosamineProtective AgentsVanillic Acid1,2-dimethylhydrazineaberrant crypt focicancer chemopreventiondiethylnitrosamineGST-P positive focivanillic acid

Identifiers

PMID34063148
PMCPMC8125109
OpenAlexW3159886166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.