Evidence map›Paper›PMID 34063131›Full record

ReviewVaccines2021

Better Pandemic Influenza Preparedness through Adjuvant Technology Transfer: Challenges and Lessons Learned.

Céline H Lemoine, Reviany V Nidom, Roland Ventura, Setyarina Indrasari, Irine Normalina, Kuncoro Puguh Santoso, Francis Derouet, Christophe Barnier-Quer, Gerrit Borchard, Nicolas Collin and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Céline H LemoineInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Rue Michel-Servet 1, 1221 Geneva, Switzerland.
Reviany V NidomProfessor Nidom Foundation, Surabaya 60298, Indonesia.
Roland VenturaVaccine Formulation Institute, Chemin des Aulx 14, 1228 Plan-les-Ouates, Switzerland.
Setyarina IndrasariProfessor Nidom Foundation, Surabaya 60298, Indonesia.
Irine NormalinaProfessor Nidom Foundation, Surabaya 60298, Indonesia.
Kuncoro Puguh SantosoProfessor Nidom Foundation, Surabaya 60298, Indonesia.
Francis DerouetCentre Laboratoire d'Epalinges (CLE), University of Lausanne, Ch. des Boveresses 155, 1011 Epalinges, Switzerland.
Christophe Barnier-QuerVaccine Formulation Laboratory, University of Lausanne, Ch. des Boveresses 155, 1066 Epalinges, Switzerland.
Gerrit BorchardInstitute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, Rue Michel-Servet 1, 1221 Geneva, Switzerland.ORCID 0000-0001-6268-2586
Nicolas CollinVaccine Formulation Institute, Chemin des Aulx 14, 1228 Plan-les-Ouates, Switzerland.
Chairul A NidomProfessor Nidom Foundation, Surabaya 60298, Indonesia.
Airlangga University · IDUniversity of Geneva · CHGlobal Alliance for Livestock Veterinary Medicines · GBUniversity of Lausanne · CH

Funding

Swiss National Science Foundation IZ07Z0_160923
6 · The paper itself

Abstract

Adequate global vaccine coverage during an influenza pandemic is essential to mitigate morbidity, mortality, and economic impact. Vaccine development and production needs to be sufficient to meet a vast global demand, requiring international cooperation and local vaccine production capacity, especially in resource-constrained countries. The use of adjuvants is one approach to augment the number of available vaccine doses and to overcome potential vaccine shortages. Appropriately selected adjuvant technologies can decrease the amount of vaccine antigen required per dose, may broaden or lengthen the conferred protection against disease, and may even allow protective single-dose vaccination. Here we describe a technology transfer collaboration between Switzerland and Indonesia that led to the establishment of a vaccine formulation platform in Surabaya which involved the transfer of equipment and expertise to enable research and development of adjuvanted vaccine formulations and delivery systems. This new Indonesian capability aims to facilitate local and regional access to know-how relating to adjuvanted vaccine formulations, thus promoting their application to local vaccine developers. In this review, we aim to share the "lessons learned" from this project to both support and inspire future scientific collaborations of a similar nature.

Indexed as

adjuvanted vaccinesglobal healthinfluenzalessons learnedpandemic preparednesstechnology transfer

Identifiers

PMID34063131
PMCPMC8148163
OpenAlexW3157328245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.