Evidence map›Paper›PMID 34063127›Full record

ArticleLife (Basel, Switzerland)2021

Herbal Extract from

Jieh-Neng Wang, Chung-Dann Kan, Lain-Tze Lee, Lynn L H Huang, Ya-Li Hsiao, Allen H Chang, Wanchun Liu, Cheng Lin, Chou-Wen Lin

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jieh-Neng WangDepartment of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70401, Taiwan.ORCID 0000-0002-7128-5344
Chung-Dann KanDepartment of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70401, Taiwan.
Lain-Tze LeeHerbal Medical Product Technology Division, Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 31057, Taiwan.
Lynn L H HuangDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 70401, Taiwan.ORCID 0000-0002-6602-7578
Ya-Li HsiaoDepartment of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70401, Taiwan.
Allen H ChangDepartment of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 70401, Taiwan.
Wanchun LiuHerbal Medical Product Technology Division, Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 31057, Taiwan.
Cheng LinHerbal Medical Product Technology Division, Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 31057, Taiwan.
Chou-Wen LinHerbal Medical Product Technology Division, Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu 31057, Taiwan.

Funding

Industrial Technology Research Institute, Taiwan Grant Nos. 9356E28200, A356E28200, and B356E22100
6 · The paper itself

Abstract

backgroundThe roots of

methodsA mouse embryonic stem (ES) cell-based model with an enhanced green fluorescent protein (eGFP) reporter driven by a cardiomyocyte-specific promoter, the α-myosin heavy chain, was constructed to evaluate the cardiogenic activity of herbal extracts. Then, herbal extracts from

resultsThe herbal extract 417W from

conclusionsThe herbal extract 417W can enhance the cardiogenic differentiation of ES cells and improve the cardiac function of infarcted hearts.

Indexed as

cardiogenesiscardiomyocytesherbal extractsmyocardial infarction

Identifiers

PMID34063127
PMCPMC8148170

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.