Evidence map›Paper›PMID 34063112›Full record

ArticleBiomedicines2021

Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse.

Maria Regoni, Letizia Zanetti, Stefano Comai, Daniela Mercatelli, Salvatore Novello, Federica Albanese, Laura Croci, Gian Giacomo Consalez, Andrea Ciammola, Flavia Valtorta and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Maria RegoniDivision of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0002-7162-7447
Letizia ZanettiDivision of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
Stefano ComaiDivision of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0002-5686-7194
Daniela MercatelliDepartment of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, 44121 Ferrara, Italy.
Salvatore NovelloDepartment of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-2157-1358
Federica AlbaneseDepartment of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, 44121 Ferrara, Italy.
Laura CrociDivision of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0002-7826-428X
Gian Giacomo ConsalezDivision of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0003-4594-6273
Andrea CiammolaDepartment of Neurology and Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, 20149 Milan, Italy.
Flavia ValtortaDivision of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
Michele MorariDepartment of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-4601-4454
Jenny SassoneDivision of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.
Vita-Salute San Raffaele University · ITUniversity of Ferrara · ITIRCCS Istituto Auxologico Italiano · ITSan Raffaele University of Rome · ITUniversity of Padua · IT

Funding

Italian Ministry of Health GR-2016-02361366Michael J. Fox Foundation for Parkinson's Research MJFF14110Telethon Foundation GGP15167
6 · The paper itself

Abstract

Mutations in the

Indexed as

cytoplasmic vacuolizationdopaminergic neuronsearly dysfunctionfiring activitymitochondriaparkinQ311X mouseParkinson’s disease

Identifiers

PMID34063112
PMCPMC8148213
OpenAlexW3157759794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.