Evidence map›Paper›PMID 34063072›Full record

ReviewMolecules (Basel, Switzerland)2021

Polymer Scaffolds for Biomedical Applications in Peripheral Nerve Reconstruction.

Meng Zhang, Ci Li, Li-Ping Zhou, Wei Pi, Pei-Xun Zhang

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  7. Electric field bridging-effect in electrified microfibrils' scaffolds.Frontiers in bioengineering and biotechnology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meng ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100083, China.
Ci LiDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100083, China.
Li-Ping ZhouBeijing Key Laboratory for Bioengineering and Sensing Technology, Daxing Research Institute, School of Chemistry & Biological Engineering, University of Science & Technology Beijing, Beijing 100083, China.
Wei PiDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100083, China.
Pei-Xun ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100083, China.

Funding

Beijing Natural Science Foundation 7212121Major R & D Program of National Ministry of Science and Technology of China 2018YFB1105504National Natural Science Foundation of China 31771322
6 · The paper itself

Abstract

The nervous system is a significant part of the human body, and peripheral nerve injury caused by trauma can cause various functional disorders. When the broken end defect is large and cannot be repaired by direct suture, small gap sutures of nerve conduits can effectively replace nerve transplantation and avoid the side effect of donor area disorders. There are many choices for nerve conduits, and natural materials and synthetic polymers have their advantages. Among them, the nerve scaffold should meet the requirements of good degradability, biocompatibility, promoting axon growth, supporting axon expansion and regeneration, and higher cell adhesion. Polymer biological scaffolds can change some shortcomings of raw materials by using electrospinning filling technology and surface modification technology to make them more suitable for nerve regeneration. Therefore, polymer scaffolds have a substantial prospect in the field of biomedicine in future. This paper reviews the application of nerve conduits in the field of repairing peripheral nerve injury, and we discuss the latest progress of materials and fabrication techniques of these polymer scaffolds.

Indexed as

Biomedical TechnologyAnimalsExtracellular MatrixHumansPeripheral NervesPolymersTissue EngineeringTissue ScaffoldsPolymersnatural and synthetic polymersnerve conduitsnerve reconstructionperipheral nerve injurypolymeric scaffold

Identifiers

PMID34063072
PMCPMC8124340

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.