Evidence map›Paper›PMID 34063041›Full record

ReviewDiagnostics (Basel, Switzerland)2021

Fatigue in Kidney Transplantation: A Systematic Review and Meta-Analysis.

Maurizio Bossola, Maria Arena, Federica Urciuolo, Manuela Antocicco, Gilda Pepe, Giovanna Elisa Calabrò, Claudia Cianfrocca, Enrico Di Stasio

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Sleep-Related Disorders in Patients with CKD and Kidney Transplant Recipients.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. SupervisedWorld journal of transplantation · 2024
    Article
  12. Correlation of objective and subjective sleep parameters with fatigue and depression in kidney transplant recipients.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maurizio BossolaDipartimento di Scienze Mediche e Chirurgiche, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.ORCID 0000-0003-1627-0235
Maria ArenaDipartimento di Scienze Mediche e Chirurgiche, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.ORCID 0000-0002-4543-3358
Federica UrciuoloDipartimento di Scienze Mediche e Chirurgiche, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Manuela AntociccoFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
Gilda PepeDipartimento di Scienze Mediche e Chirurgiche, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Giovanna Elisa CalabròDipartimento di Scienze della Vita e Sanità Pubblica, Sezione di Igiene, Università Cattolica del Sacro Cuore, 00168 Roma, Italy.
Claudia CianfroccaDipartimento di Biomedicina e Prevenzione, Università degli Studi di Roma "Tor Vergata", 00133 Roma, Italy.
Enrico Di StasioFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
Università Cattolica del Sacro Cuore · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fatigue is still present in up to 40-50% of kidney transplant recipients (KTR), the results of studies comparing the prevalence among patients on hemodialysis (HD) and KTR led to conflicting results. Fatigue correlates include inflammation, symptoms of depression, sleep disorders and obesity. Fatigue in KTR leads to significant functional impairment, it is common among KTR poorly adherent to immunosuppressive therapy and is associated with a serious deterioration of quality of life. The following databases were searched for relevant studies up to November 2020: Medline, PubMed, Web of Science and the Cochrane Library. Several studies have compared the prevalence and severity of fatigue between KTR and hemodialysis or healthy patients. They have shown that fatigue determines a significant functional deterioration with less chance of having a paid job and a significant change in quality of life. The aim of the review is to report methods to assess fatigue and its prevalence in KTR patients, compared to HD subjects and define the effects of fatigue on health status and daily life. There is no evidence of studies on the treatment of this symptom in KTR. Efforts to identify and treat fatigue should be a priority to improve the quality of life of KTR.

Indexed as

assessmentfatiguekidney transplant recipientspatients on hemodialysis

Identifiers

PMID34063041
PMCPMC8147914
OpenAlexW3157652045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.