Evidence map›Paper›PMID 34062957›Full record

Trial reportCells2021

Differential Effects of Angiotensin-II Compared to Phenylephrine on Arterial Stiffness and Hemodynamics: A Placebo-Controlled Study in Healthy Humans.

Klaas F Franzen, Moritz Meusel, Julia Engel, Tamara Röcker, Daniel Drömann, Friedhelm Sayk

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Klaas F FranzenMedizinische Klinik III, Universitätsklinikum Schleswig-Holstein, 23538 Lübeck, Germany.
Moritz MeuselMedizinische Klinik II, Universitätsklinikum Schleswig-Holstein, 23538 Lübeck, Germany.ORCID 0000-0002-8473-3601
Julia EngelMedizinische Klinik I, Universitätsklinikum Schleswig-Holstein, 23538 Lübeck, Germany.ORCID 0000-0001-6416-6876
Tamara RöckerMedizinische Klinik I, Universitätsklinikum Schleswig-Holstein, 23538 Lübeck, Germany.
Daniel DrömannMedizinische Klinik III, Universitätsklinikum Schleswig-Holstein, 23538 Lübeck, Germany.
Friedhelm SaykMedizinische Klinik I, Universitätsklinikum Schleswig-Holstein, 23538 Lübeck, Germany.
University Hospital Schleswig-Holstein · DE

Funding

Deutsche Forschungsgemeinschaft SFB 654 Project B4
6 · The paper itself

Abstract

The α

Indexed as

AdultAngiotensin IIBaroreflexEndothelium, VascularFemaleHealthy VolunteersHemodynamicsHumansMalePhenylephrineVascular StiffnessVasoconstrictor AgentsAngiotensin IIPhenylephrineVasoconstrictor AgentsAngiotensin IIarterial stiffnessaugmentation indexbaroreflexphenylephrinepulse wave velocityα1-adrenoceptor

Identifiers

PMID34062957
PMCPMC8147945
OpenAlexW3157769075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.