Evidence map›Paper›PMID 34062918›Full record

ArticleBiomolecules2021

Combined Analytical Approaches to Standardize and Characterize Biomaterials Formulations: Application to Chitosan-Gelatin Cross-Linked Hydrogels.

Sofia Magli, Lorenzo Rossi, Cesare Consentino, Sabrina Bertini, Francesco Nicotra, Laura Russo

Abstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sofia MagliDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0003-2413-5375
Lorenzo RossiDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0001-7039-8593
Cesare ConsentinoG. Ronzoni Institute for Chemical and Biochemical Research, 20126 Milan, Italy.
Sabrina BertiniG. Ronzoni Institute for Chemical and Biochemical Research, 20126 Milan, Italy.ORCID 0000-0003-1714-5823
Francesco NicotraDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0003-1008-196X
Laura RussoDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0002-5914-766X

Funding

Horizon 2020 Framework Programme H2020-NMBP-15-2017-GA-760986Ministero della Salute RF-2016-02362946Regione Lombardia Azione I.1.b.1.3-IMMUN-HUB - Sviluppo di nuove molecole di seconda generazione per immunoterapia oncologica.
6 · The paper itself

Abstract

A protocol based on the combination of different analytical methodologies is proposed to standardize the experimental conditions for reproducible formulations of hybrid hydrogels. The final hybrid material, based on the combination of gelatin and chitosan functionalized with methylfuran and cross-linked with 4-arm-PEG-maleimide, is able to mimic role, dynamism, and structural complexity of the extracellular matrix. Physical-chemical properties of starting polymers and finals constructs were characterized exploiting the combination of HP-SEC-TDA, UV, FT-IR, NMR, and TGA.

Indexed as

Biocompatible MaterialsChitosanDrug CompoundingFuransGelatinHydrogelsMaleimidesMolecular StructureBiocompatible MaterialsChitosanFuransGelatinHydrogelsMaleimideschitosanDiels Alderextracellular matrixgelatinhybrid biomaterialshydrogels

Identifiers

PMID34062918
PMCPMC8147276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.