ArticleInternational journal of molecular sciences2021
In Vivo Analysis of the Biocompatibility and Bone Healing Capacity of a Novel Bone Grafting Material Combined with Hyaluronic Acid.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06783517 (Evaluation of Hyaluronic Acid in Addition to Xenograft Material in Treatment Peri-implant Bony Defects in Immediate Implant Placement Within Maxillary Esthetic Zone), which is not on this map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Hyaluronic Acid in Addition to Xenograft Material in Treatment Peri-implant Bony Defects in Immediate Implant Placement Within Maxillary Esthetic Zone
Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Histomorphometric Evaluation of Socket Preservation Healing Using Xenogeneic Bone Substitute Combined with Statin: A Prospective Split-Mouth Clinical Pilot Study.Acta stomatologica Croatica · 2026Article
- Calcium ionic replacement in sodium trimetaphosphate particles: a novel strategy for bone tissue engineering.Journal of materials science. Materials in medicine · 2026Article
- Antibody-Integrated Solid-to-Gel Microfilm for Protection Against Botulinum Neurotoxin Type A.Gels (Basel, Switzerland) · 2025Article
- Types of Bone Substitutes and Their Application in Regenerative Medicine: A Systematic Review.Journal of functional biomaterials · 2025Review
- Histological and histomorphometric evaluation of natural bovine bone substitute with hyaluronate in socket preservation-a report of three cases.Journal of materials science. Materials in medicine · 2025Article
- Clinical Effectiveness of Bee Venom Acupuncture for Bone Fractures and Potential Mechanisms: A Narrative Overview.Toxins · 2024Review
- Biphasic bone substitutes coated with PLGA incorporating therapeutic ions SrFrontiers in bioengineering and biotechnology · 2024Article
- First Clinical Case Report of a Xenograft-Allograft Combination for Alveolar Ridge Augmentation Using a Bovine Bone Substitute Material with Hyaluronate (CeraboneJournal of clinical medicine · 2023Article
- Regeneration of Buccal Wall Defects after Tooth Extraction with Biphasic Calcium Phosphate in Injectable Form vs. Bovine Xenograft: A Randomized Controlled Clinical Trial.Dentistry journal · 2023Article
- Evaluation between Biodegradable Magnesium Metal GBR Membrane and Bovine Graft with or without Hyaluronate.Membranes · 2023Article
- Analyses of the Cellular Interactions between the Ossification of Collagen-Based Barrier Membranes and the Underlying Bone Defects.International journal of molecular sciences · 2023Article
- Calcium-to-phosphorus releasing ratio affects osteoinductivity and osteoconductivity of calcium phosphate bioceramics in bone tissue engineering.Biomedical engineering online · 2023Article
- Article
- In Vivo Analysis of the Regeneration Capacity and Immune Response to Xenogeneic and Synthetic Bone Substitute Materials.International journal of molecular sciences · 2022Article
- In Vivo Biocompatibility Analysis of a Novel Barrier Membrane Based on Bovine Dermis-Derived Collagen for Guided Bone Regeneration (GBR).Membranes · 2022Article
- In Vivo Biocompatibility Investigation of an Injectable Calcium Carbonate (Vaterite) as a Bone Substitute including Compositional Analysis via SEM-EDX Technology.International journal of molecular sciences · 2022Article
- Novel Histomorphometrical Approach to Evaluate the Integration Pattern and Functionality of Barrier Membranes.Dentistry journal · 2021Article
- Article
- Validation of the Chick Chorioallantoic Membrane (CAM) Model for Biocompatibility Analysis of Biomaterials in the Context of the 3R-cascade: A Pilot Study.In vivo (Athens, Greece)Article
- Composite Coating-driven Regulation ofIn vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present in vivo study analyses both the inflammatory tissue reactions and the bone healing capacity of a newly developed bone substitute material (BSM) based on xenogeneic bone substitute granules combined with hyaluronate (HY) as a water-binding molecule. The results of the hyaluronate containing bone substitute material (BSM) were compared to a control xenogeneic BSM of the same chemical composition and a sham operation group up to 16 weeks
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.