Evidence map›Paper›PMID 34062854›Full record

ArticleGenes2021

The Cause of Hereditary Hearing Loss in

Dana Safka Brozkova, Anna Uhrova Meszarosova, Petra Lassuthova, Lukáš Varga, David Staněk, Silvia Borecká, Jana Laštůvková, Vlasta Čejnová, Dagmar Rašková, Filip Lhota and 2 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
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  8. Review
  9. 3D Chromatin Organization Involving MEIS1 Factor in theInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Analysis of GJB2 Gene Mutations in 1330 Deafness Cases of Major Ethnic Groups in Northwest China.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Dana Safka BrozkovaNeurogenetic laboratory, Department of Paediatric Neurology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, 15006 Prague, Czech Republic.ORCID 0000-0002-0572-7239
Anna Uhrova MeszarosovaNeurogenetic laboratory, Department of Paediatric Neurology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, 15006 Prague, Czech Republic.
Petra LassuthovaNeurogenetic laboratory, Department of Paediatric Neurology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, 15006 Prague, Czech Republic.
Lukáš VargaDepartment of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine and University Hospital, Comenius University, 85107 Bratislava, Slovakia.
David StaněkNeurogenetic laboratory, Department of Paediatric Neurology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, 15006 Prague, Czech Republic.
Silvia BoreckáDiabgene Laboratory, Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, 84505 Bratislava, Slovakia.
Jana LaštůvkováDepartment of Medical Genetics, Masaryk Hospital in Usti nad Labem, Regional Health Corporation, 40011 Ústí nad Labem, Czech Republic.
Vlasta ČejnováDepartment of Medical Genetics, Masaryk Hospital in Usti nad Labem, Regional Health Corporation, 40011 Ústí nad Labem, Czech Republic.
Dagmar RaškováCentre for Medical Genetics and Reproductive Medicine GENNET, 17000 Prague, Czech Republic.
Filip LhotaCentre for Medical Genetics and Reproductive Medicine GENNET, 17000 Prague, Czech Republic.
Daniela GašperíkováDiabgene Laboratory, Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, 84505 Bratislava, Slovakia.ORCID 0000-0002-5725-6424
Pavel SeemanNeurogenetic laboratory, Department of Paediatric Neurology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, 15006 Prague, Czech Republic.
Charles University · CZSlovak Academy of Sciences · SKKrajská Zdravotní · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hearing loss is a genetically heterogeneous sensory defect, and the frequent causes are biallelic pathogenic variants in the

Indexed as

Connexin 26Gene FrequencyHearing Loss, SensorineuralHeterozygoteHumansMutationConnexin 26GJB2 protein, humanDFNB1 regionGJB2 monoallelic varianthearing lossnext generation sequencing

Identifiers

PMID34062854
PMCPMC8147375
OpenAlexW3159187155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.