ArticleNeuroImage2021
Emerging ethical issues raised by highly portable MRI research in remote and resource-limited international settings.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 61 citations in OpenAlex.
- Feasibility of and experience using a portable MRI scanner in the neonatal intensive care unit.Archives of disease in childhood. Fetal and neonatal edition · 2023Trial
- Article
- Altered neurostructural development in magnetic resonance imaging-negative pediatric epilepsy: A large-scale multicenter study of 1919 children.Epilepsia · 2026Article
- Decoding real-world visual scenes from alpha and gamma band flicker evoked oscillations in human EEG.Scientific reports · 2026Article
- Feasibility and Clinical Utility of Low-Field Magnetic Resonance Imaging in Critically Ill Children: An Experience from Pakistan.Neurocritical care · 2026Article
- Clinical translation of fluid, imaging, and digital biomarkers for Alzheimer's disease.Alzheimer's research & therapy · 2026Review
- Ultra-low-field MRI: a David versus Goliath challenge in modern imaging.La Radiologia medica · 2025Review
- Feasibility and acceptability of magnetic resonance imaging and electroencephalography for child neurodevelopmental research in rural Ethiopia.Frontiers in public health · 2025Article
- Implementation of mobile EEG for resting-state and visual evoked potentials in young children in rural Ethiopia.Frontiers in human neuroscience · 2025Article
- Revolutionizing Brain Research Using Portable MRI in Field Settings: Public Perspectives on the Ethical and Legal Challenges.Neuroethics · 2025Article
- Feasibility and Usability of Low-Field Magnetic Resonance Imaging for Pediatric Neuroimaging in Low- and Middle-Income Countries: A Qualitative Study.Medical devices (Auckland, N.Z.) · 2025Article
- Initial insights into post-contrast enhancement in ultra-low-field MRI: Case Report.Frontiers in neuroimaging · 2025Article
- Scientists' perspectives on ethical issues in research with emerging portable neuroimaging technology: The need for guidance on ethical, legal, and societal implications (ELSI).NMR in biomedicine · 2024Article
- Fast, high-quality, and unshielded 0.2 T low-field mobile MRI using minimal hardware resources.Magma (New York, N.Y.) · 2024Article
- Proof of concept: Portable ultra-low-field magnetic resonance imaging for the diagnosis of epileptogenic brain pathologies.Epilepsia · 2024Article
- Review
- Article
- Bridging the gap: improving correspondence between low-field and high-field magnetic resonance images in young people.Frontiers in neurology · 2024Article
- Applications, limitations and advancements of ultra-low-field magnetic resonance imaging: A scoping review.Surgical neurology international · 2024Article
- Can biosampling really be "non-invasive"? An examination of the socially invasive nature of physically non-invasive biosampling in urban and rural Malawi.Global bioethics = Problemi di bioetica · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 11 institutions in 6 countries.
Funding
Abstract
Smaller, more affordable, and more portable MRI brain scanners offer exciting opportunities to address unmet research needs and long-standing health inequities in remote and resource-limited international settings. Field-based neuroimaging research in low- and middle-income countries (LMICs) can improve local capacity to conduct both structural and functional neuroscience studies, expand knowledge of brain injury and neuropsychiatric and neurodevelopmental disorders, and ultimately improve the timeliness and quality of clinical diagnosis and treatment around the globe. Facilitating MRI research in remote settings can also diversify reference databases in neuroscience, improve understanding of brain development and degeneration across the lifespan in diverse populations, and help to create reliable measurements of infant and child development. These deeper understandings can lead to new strategies for collaborating with communities to mitigate and hopefully overcome challenges that negatively impact brain development and quality of life. Despite the potential importance of research using highly portable MRI in remote and resource-limited settings, there is little analysis of the attendant ethical, legal, and social issues (ELSI). To begin addressing this gap, this paper presents findings from the first phase of an envisioned multi-staged and iterative approach for creating ethical and legal guidance in a complex global landscape. Section 1 provides a brief introduction to the emerging technology for field-based MRI research. Section 2 presents our methodology for generating plausible use cases for MRI research in remote and resource-limited settings and identifying associated ELSI issues. Section 3 analyzes core ELSI issues in designing and conducting field-based MRI research in remote, resource-limited settings and offers recommendations. We argue that a guiding principle for field-based MRI research in these contexts should be including local communities and research participants throughout the research process in order to create sustained local value. Section 4 presents a recommended path for the next phase of work that could further adapt these use cases, address ethical and legal issues, and co-develop guidance in partnership with local communities.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.