Evidence map›Paper›PMID 34062085›Full record

Trial reportPharmaceutical biology2021

Effect of fermented milk on upper respiratory tract infection in adults who lived in the haze area of Northern China: a randomized clinical trial.

Hong Zhang, Junli Miao, Miya Su, Bryan Y Liu, Zhenmin Liu

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pharmaceutical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. The Effect ofMicroorganisms · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hong ZhangDepartment of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Junli MiaoDairy Research Institute, Bright Dairy & Food Co., Ltd, Shanghai, China.
Miya SuDairy Research Institute, Bright Dairy & Food Co., Ltd, Shanghai, China.
Bryan Y LiuCollege of Biotechnology, East China University of Science and Technology, Shanghai, China.
Zhenmin LiuDairy Research Institute, Bright Dairy & Food Co., Ltd, Shanghai, China.
Beijing Chao-Yang Hospital · CNEast China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextUpper respiratory tract infection (URTI) is the most common illness in humans. Fermented milk containing probiotics can mitigate URTI symptoms.

objectiveThis study tests the effect of fermented milk (Qingrun), a yogurt supplemented with MATERIALS AND

methodsA total of 136 subjects were enrolled in the study at the baseline and randomized to consume either control yogurt or Qingrun yogurt (250 g) once daily for 12 weeks. The duration and severity of URTI were evaluated by the Wisconsin Upper Respiratory Symptom Survey-24. Blood and faecal samples were collected at the baseline and post-intervention, to determine the changes of immune biomarkers.

resultsQingrun yogurt significantly reduced the incidence of the common cold (OR, 0.38; 95% CI, 0.17-0.81;

conclusionsQingrun yogurt showed a protective effect against URTI in adults, suggesting that the use of yogurt with probiotics could be a promising dietary supplement for mitigating URTI.

Indexed as

BifidobacteriumDietary SupplementsAdultAir PollutionChinaDouble-Blind MethodFemaleFermentationHumansMaleMiddle AgedProbioticsRespiratory Tract InfectionsYogurtBifidobacterium animalis subsp. lactis Bl-04Probioticssmoker

Identifiers

PMID34062085
PMCPMC8172217
OpenAlexW3165807103

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.