Evidence map›Paper›PMID 34062039›Full record

ReviewChembiochem : a European journal of chemical biology2021

Lessons in Organic Fluorescent Probe Discovery.

Sachin B Wagh, Vladimir A Maslivetc, James J La Clair, Alexander Kornienko

Abstract readReview
In one paragraph

Review in Chembiochem : a European journal of chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. The Evolution of Fluorescein into A Potential Theranostic Tool.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  4. Review
  5. RSC advances · 2025
    Article
  6. Review
  7. Synthesis of Pyridin-1(2Molecules (Basel, Switzerland) · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sachin B WaghThe Department of Chemistry and Biochemistry, Texas State University, San Marcos, USA.ORCID 0000-0002-4123-5143
Vladimir A MaslivetcThe Department of Chemistry and Biochemistry, Texas State University, San Marcos, USA.
James J La ClairXenobe Research Institute, P. O. Box 3052, San Diego, CA, 92163-1062, USA.ORCID 0000-0001-6500-4107
Alexander KornienkoThe Department of Chemistry and Biochemistry, Texas State University, San Marcos, USA.ORCID 0000-0003-2041-7367

Funding

Acid-Sensitive Glioblastoma Prodrugs Derived from Ophiobolin AR15CA227680 · NCI · TEXAS STATE UNIVERSITY · PI KORNIENKO, ALEXANDER · 2019 to 2019
$462k
Tandem Discovery of Drug Leads and Targets via Paal-Knorr reactionR21GM131717 · NIGMS · TEXAS STATE UNIVERSITY · PI KORNIENKO, ALEXANDER, LA CLAIR, JAMES J · 2019 to 2020
$374k
NCI NIH HHS R15 CA227680NIGMS NIH HHS R21 GM131717NIH HHS 1R15CA227680NIH HHS 5R21GM131717
6 · The paper itself

Abstract

Fluorescent probes have gained profound use in biotechnology, drug discovery, medical diagnostics, molecular and cell biology. The development of methods for the translation of fluorophores into fluorescent probes continues to be a robust field for medicinal chemists and chemical biologists, alike. Access to new experimental designs has enabled molecular diversification and led to the identification of new approaches to probe discovery. This review provides a synopsis of the recent lessons in modern fluorescent probe discovery.

Indexed as

Drug DiscoveryFluorescent DyesHumansOrganic ChemicalsFluorescent DyesOrganic Chemicalschemical biologyfluorescencefluorophoresmolecular probessensors

Identifiers

PMID34062039
PMCPMC8595615

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.