ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2021
The Longitudinal Association of Vision Impairment With Transitions to Cognitive Impairment and Dementia: Findings From the Aging, Demographics and Memory Study.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The validity of visual and hearing impairment in predicting dementia and cognitive impairment in older adults: a systematic review and meta-analysis.Frontiers in aging neuroscience · 2025Pooled it
- Sensory Difficulty, Social and Physical Activity, and Dementia Risk Among Older Adults.Journal of aging and health · 2026Article
- Retinal proteome changes mirror brain pathology and reveal synaptic and cytoskeletal dysfunction in Alzheimer's disease.Acta neuropathologica · 2026Article
- Sensory Difficulty and Assistive Device Use Among Older U.S. Immigrants: Differences by Region of Origin.Research on aging · 2026Article
- Sensorimotor Impairment and Incident Dementia in the US Medicare Beneficiaries.Journal of the American Geriatrics Society · 2026Article
- Sensory impairments and cognitive impairment among Mexican American older adults: nativity differences.Aging & mental health · 2026Article
- Visual Impairment and Cognitive Function in Aging Adults: Sex and Age Differences in Mediating Effect of Social Isolation and Depression.American journal of ophthalmology · 2025Article
- Color memory as a diagnostic test for mild cognitive impairment and early stage of Alzheimer's disease.Frontiers in neurology · 2025Article
- Social engagement and cognitive impairment among nursing home residents: The role of sensory impairment.Archives of gerontology and geriatrics · 2024Article
- Vision Impairment and Frailty Among Mexican American Older Adults: A Longitudinal Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024Article
- Associations Between Self-Reported Visual and Hearing Functioning and Cognitive Function Among Hispanics/Latino: Hispanic Community Health Study.Innovation in aging · 2024Article
- Association Between Contrast Sensitivity and Physical Function in Cognitively Healthy Older Adults: The Brain Networks and Mobility Function Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Association of age-related eye diseases with cognitive frailty in older adults: a population-based study.Aging clinical and experimental research · 2023Article
- Visual and cognitive functioning among older adults with low vision before vision rehabilitation: A pilot study.Frontiers in psychology · 2023Article
- Patterns of sleep disturbances across stages of cognitive decline.International journal of geriatric psychiatry · 2023Article
- Interactions between the apolipoprotein E4 gene and modifiable risk factors for cognitive impairment: a nationally representative panel study.BMC geriatrics · 2022Article
- Use and Perceptions of Advanced Driver Assistance Systems by Older Drivers With and Without Age-Related Macular Degeneration.Translational vision science & technology · 2022Article
- Severity and progression of visual impairment and risk of dementia.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Abstract
backgroundVision impairment (VI) is associated with incident cognitive decline and dementia. However, it is not known whether VI is associated only with the transition to cognitive impairment, or whether it is also associated with later transitions to dementia.
methodsWe used data from the population-based Aging, Demographics and Memory Study (ADAMS) to investigate the association of visual acuity impairment (VI; defined as binocular presenting visual acuity <20/40) with transitions from cognitively normal to cognitive impairment no dementia (CIND) and from CIND to dementia. Multivariable Cox proportional hazards models and logistic regression were used to model the association of VI with cognitive transitions, adjusted for covariates.
resultsThere were 351 participants included in this study (weighted percentages: 45% male, 64% age 70-79 years) with a mean follow-up time of 4.1 years. In a multivariable model, the hazard of dementia was elevated among those with VI (hazard ratio = 1.63, 95% confidence interval = 1.04-2.58). Participants with VI had a greater hazard of transitioning from cognitively normal to CIND (hazard ratio = 1.86, 95% confidence interval = 1.09-3.18). However, among those with CIND and VI a similar percentage transitioned to dementia (48%) and remained CIND (52%); there was no significant association between VI and transitioning from CIND to dementia (hazard ratio = 0.94, 95% confidence interval = 0.56-1.55). Using logistic regression models, the same associations between VI and cognitive transitions were identified.
conclusionsPoor vision is associated with the development of CIND. The association of VI and dementia appears to be due to the higher risk of dementia among individuals with CIND. Findings may inform the design of future interventional studies.
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