Evidence map›Paper›PMID 34061731›Full record

ArticleIEEE transactions on bio-medical engineering2021

Modeling of Glioma Growth With Mass Effect by Longitudinal Magnetic Resonance Imaging.

Birkan Tunc, David Hormuth, George Biros, Thomas E Yankeelov

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Dynamic image-informed selection of biomechanical tumor growth models.Biomechanics and modeling in mechanobiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Birkan Tunc
David Hormuth
George Biros
Thomas E Yankeelov
Livestrong Foundation · USThe University of Texas at Austin · USYeditepe University · TR

Funding

Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
Image Driven Multi-Scale Modeling to Predict Treatment Response in Breast CancerU01CA174706 · NCI · VANDERBILT UNIVERSITY · PI QUARANTA, VITO, YANKEELOV, THOMAS E · 2013 to 2018
$2.5M
Evaluation and Validation of Imaging Biomarkers of Tumor Response to TreatmentR01CA138599 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MCINTYRE, JAMES OLIVER · 2010 to 2015
$2.2M
NCI NIH HHS R01 CA138599NCI NIH HHS U01 CA174706NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

It is well-known that expanding glioblastomas typically induce significant deformations of the surrounding parenchyma (i.e., the so-called "mass effect"). In this study, we evaluate the performance of three mathematical models of tumor growth: 1) a reaction-diffusion-advection model which accounts for mass effect (RDAM), 2) a reaction-diffusion model with mass effect that is consistent only in the case of small deformations (RDM), and 3) a reaction-diffusion model that does not include the mass effect (RD). The models were calibrated with magnetic resonance imaging (MRI) data obtained during tumor development in a murine model of glioma (n = 9). We obtained T

Indexed as

Brain NeoplasmsGlioblastomaGliomaAnimalsDiffusion Magnetic Resonance ImagingMagnetic Resonance ImagingMice

Identifiers

PMID34061731
PMCPMC8604780
OpenAlexW3164314236

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.