Evidence map›Paper›PMID 34061296›Full record

ArticleNatural products and bioprospecting2021

Sesquiterpenoids and 2-(2-Phenylethyl)chromone Derivatives from the Resinous Heartwood of Aquilaria sinensis.

Shu-Ya Wei, Dong-Bao Hu, Meng-Yuan Xia, Ji-Feng Luo, Hui Yan, Jing-Hua Yang, Yun-Song Wang, Yue-Hu Wang

Open access · diamondAbstract read
In one paragraph

Article in Natural products and bioprospecting, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  3. Article
  4. Article
  5. Five new sesquiterpenoids from agarwood ofBeilstein journal of organic chemistry · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Shu-Ya Wei *Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, School of Pharmacy, Yunnan University, Kunming, 650091, People's Republic of China.
Dong-Bao Hu *School of Chemical Biology and Environment, Yuxi Normal University, Yuxi, 653100, People's Republic of China.
Meng-Yuan XiaKey Laboratory of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, and State Key Laboratory of Phytochemistry and Plant Resources in West China, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.
Ji-Feng LuoKey Laboratory of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, and State Key Laboratory of Phytochemistry and Plant Resources in West China, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.
Hui YanKey Laboratory of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, and State Key Laboratory of Phytochemistry and Plant Resources in West China, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China.
Jing-Hua YangKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, School of Pharmacy, Yunnan University, Kunming, 650091, People's Republic of China.
Yun-Song WangKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, School of Pharmacy, Yunnan University, Kunming, 650091, People's Republic of China. wangys@ynu.edu.cn.
Yue-Hu WangKey Laboratory of Economic Plants and Biotechnology, Yunnan Key Laboratory for Wild Plant Resources, and State Key Laboratory of Phytochemistry and Plant Resources in West China, Chinese Academy of Sciences, Kunming, 650201, People's Republic of China. wangyuehu@mail.kib.ac.cn.ORCID http://orcid.org/0000-0002-5327-457X
Kunming Institute of Botany · CNYunnan University · CNYuxi Normal University · CN

Funding

Joint Special Project of Local Undergraduate Universities in Yunnan Province, China 2018FH001-024National Natural Science Foundation of China 21462048National Natural Science Foundation of China 21662040National Natural Science Foundation of China 31960480National Natural Science Foundation of China 81960629
6 · The paper itself

Abstract

One novel spirolactone, aquilarisinolide (1), three new sesquiterpenoids, (2R,4S,5R,7R)-2-hydroxyeremophila-9,11-dien-8-one (2), (1R,4S,5S,7R,11R)-13-hydroxyepidaphnauran-9-en-8-one (3), and (4R,5S,7R,8S,10S,13R)-8,13-dihydroxyrotunda-1,11-dien-3-one (4), together with 13 known compounds (5-17) were isolated from the resinous heartwood of Aquilaria sinensis (Thymelaeaceae). The structures of the new compounds were elucidated based on the analysis of NMR and MS data and theoretical calculations their ECD spectra. The isolated compounds were evaluated for their protective activities against PC12 cell injury induced by corticosterone (CORT) and 1-methyl-4-phenylpyridine ion (MPP

Indexed as

2-(2-phenylethyl)chromonesAquilaria sinensisNeuroprotectiveSesquiterpenoidsThymelaeaceae

Identifiers

PMID34061296
PMCPMC8390629
OpenAlexW3165375670

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.